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GERBER LECTURE
GUEST SPEAKER ANNOUNCED
The twelfth annual Dr. and Mrs. Michael A. Gerber Memorial Lecture will be delivered by Dr. George K. Michalopoulos, Chairman of the Department of Pathology at the University of Pittsburgh. Dr. Michalopoulos is a graduate of the Athens School of Medicine and has served as Associate Vice Chancellor for Health Sciences and Interim Dean for the University of Pittsburgh School of Medicine. An avid researcher, Dr. Michalopoulos has been widely published in peer reviewed journals. His areas of interest in research target growth factors and receptors in hepatocytes; hepatic carcinoSee Gerber, p. 2

Dr. George K. Michalopoulos, 2011 Dr. and Mrs. Michael A. Gerber Memorial Lecture Guest Speaker

AASLD CONFERENCE
Four posters representing research efforts of the Pathology Department were presented at the 61st annual meeting of the American As-

sociation for the Study of Liver Dis- Conference. eases held in Boston last late October to early November. Attending See Liver, p.2

Drs. Chang Han & Feyza Gunduz (left) at AASLD

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genesis and mechanisms leading to the assembly of hepatic tissue. Held in conjunction with Tulane (Above) The late Dr. University Health Michael A. Gerber, Sciences Research former Chairman of Days (April 6-7, the Department of 2011), the Gerber Pathology and Labo- Lecture will be given ratory Medicine. at 12:00 noon on April 6, 2011 in Room 6065 of the School of Medicine. A member of several professional organizations, Dr. Michalopoulos has been a consultant for several pharmaceutical and biotechnology organizations. Co-founder of Kytaron, Inc., described as a biotech company, his efforts include building small tissues in cultures. He and his colleagues have invested and patented several new lines of biotechnology.

Dr. Byron Crawford, Vice Chairman (left) was recently named the Liaison between the CAP Surgical Pathology Committee and the Association of Directors of Anatomical and Surgical Pathology. Dr. Crawford attended the annual CAP meeting held last November in Chicago where his new position was announced. LIVER (continued)
the conference were Drs. Srikanta Dash, Chang Han and Feyza Gunduz. Of the 2,047 submitted abstracts, only 200 were given the AASLD Presidential Poster of Distinction Award. The poster, mPGES-1 accelerates hepatocellular carcinoma cell growth through activation of EGR-1 and beta-catenin, the work of Drs. Tong Wu, Han and Dongdong Lu, was a recipient of the PresidenDr. Srikanta Dash stands by a tial Poster of Distinction Award. poster submission at the 61st annual AASLD Conference in For a complete list of posters presented by Pathology Boston (October 29 faculty, see Publications on page 8. November 2, 2010).

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YOUR ATTENTION, PLEASE!

CORRECTION In the Autumn 2010 issue of the newsletter, we incorrectly reported that Hematopathology Fellow, Dr. Richard Iverson (seen right) held an M.D. degree. Dr. Iversons actual degree is a Doctor of Osteopathy, or D.O.

2010 HEART WALK The Pathology Department raised $490.00 for the Annual American Heart Association Heart Walk Drive held last November at Audubon Park. Below are members of the Heart Walk Team. Absent from picture are team members Dr. Tong Wu and Jeanne Frois. Back Row, L to R: Rabah Qadir, Tyler Heath, Dr. Tim Peterson; Front Row, L to R: Ximena Vanegas Qadir, Mallory Heath, Charlene Peterson.

Richard Iverson, D.O.

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Editors Note: Dr. Philip Daroca, historian of the Pathology Department, received this letter from a descendant of the recipient. The reply from former Chairman, the late Dr. Charles Dunlap reveals

THE WAY WE WERE

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PUBLICATIONS

Adeyi OA, Costa G, Abu-Elmagd K, Wu, T. Rotavirus infection in adult small intestine allografts: a clinicopathological study of a cohort of 23 patients. Am Journal Transplant. December 2010; 10 (12): 2683-9. PM ID: 21114645 Lin Z, Xu G, Deng N, Taylor C, Zhu D, Flemington E. Quantitative and Qualitative RNA-seq-based evaluation of Epstein-Barr Virus transcription in Type I latency Burkitts lymphoma cells. J Virol. December 2010; 84 (24): 13053-8. Epub October 13, 2010. PM ID: 20943983 Lin Z, Flemington E. miRNAs in the pathogenesis of oncogenic human viruses. Cancer Lett. October 11, 2010. (Epub ahead of print) PM ID: 20943311 Guenter J, Cameron J, Nguyen H, Wang Y, Sullivan D, Shan B, Lasky JA, Flemington E, Morris G. Modulation of lung inflammation by the Epstein-Barr Virus protein Zta. Am J Physiol of Lung Cell Mol Physiol. December 2010; 299 (6): L771-84. Epub Septpember 3, 2010. PM ID: 20817778 Kandil E, Abdel Khalek M, Alabbas H, Daroca P, Thethi T, Friedlander P, Leblanc R, Abdullah O, Jaffe B, Crawford B. Black thyroid associated with thyroid carcinoma. Int J. Endocrinol. 2010; 2010:68:681847. Epub November 23, 2010. PM ID: 21113440 Poat B, Hazari S, Chandra P, Gunduz F, Balart L, Alvarez X, Zhang Y, Holtzman M, Dash S. Correction: SH2 modified STAT 1 induces HLA-I expression and improves IFN-y signaling in IFN-a resistant HCV replicon cells. PLoS One. November 27, 2010; 5 (11). doi: 10.1371/annotation/ff8fe1fe36ae-43fe9350-8ba2f191331a. PM ID: 21124811

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Hazari S, Hefler H, Chandra P, Poat B, Gunduz F, Ooms T, Wu T, Balart L, Dash S. Hepatocellular carcinoma xenograft supports HCV replication: A mouse model for evaluating antivirals. World Journal of Gastroenterology 2011. January 21; 17(3): 300-312. PM ID: 21253388 Han C, Bowel W, Ly G, Demetris A, Michalopoulos G and Wu T. Cysto lic phospholipase A2alpha and PPAR-gammar signaling path way counteracts TGF-beta-mediated inhibition of primary and transformed hepatocyte growth. Hepatology. 2010; 52(2): 644-655.

Han C, Li G, Huang S, Wu T. Activation of STAT3 by cPLA2alpha and PPARdelta. Hepatology 2010, 52 (4): 946A. Presented @ AASLD, OctoberNovember 2010. Lu D, Han C, Wu T. Microsomal prostaglandin E sunthase-1 (mPGES-1) is a novel oncogene that promotes cholangiocarcinogenesis. Hepatology 2010, 52 (4): 937A. Presented @ AASLD, OctoberNovember 2010.

Lu D, Han C, Wu T. 15-PDGH is a key tumor suppressor that inhibits cholangiocarcinogenesis. Hepatology 2010, 52(4): 937 A. Presented @ AASLD, OctoberNovember 2010. Lu D, Han C, Wu T. mPGES-1 accelerates hepatocellular carcinoma cell growth through activation of EGR-1 and beta-catenin. Hepatology 2010, 52(4): 1134A. Presented @ AASLD , OctoberNovember 2010.

T ULANE U NIVERSITY H EALTH S CIENCES C ENTER D EPARTMENT OF P ATHOLOGY AND L ABORATORY M EDICINE

TRIBUTE Former Chairman, Dr. John Krause was recently honored for distinguished service as a pathology educator by ASCP that bestowed upon him the H.P. Smith Award. Outstanding achievements in imparting the knowledge of pathology aside, Dr. Krause successfully faced the challenge of rebuilding the TUHSC Pathology Department, Residency Program, and Hospital Laboratories after the devastation of Hurricane Katrina. In 2009, Dr. Krause joined the faculty of Baylor University Medical Center in Dallas where he began their first hematology fellowship program. In addition to many publications, Dr. Krause has likewise educated over 250 residents in the study of Pathology.

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VALENTINE S DAY , MARDI GRAS , AND ST .

P ATRICK S

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ABOUT US
Editor in Chief, PATHWAYS Quarterly is a newsletter pubManaging Editor, lished by the Depart- and Production Manment of Pathology ager: and Laboratory MediJeanne Frois cine of the Tulane Phone: 504-988University Health Sci1170 ences Center. Contact: Contributors to this issue were: Drs. Tong Wu, Byron Crawford, Philip Daroca, Chang Han, Feyza Gunduz, and Jeanne Frois.
jfrois@Tulane.edu