Drug Information Center.

Faculty of Pharmacy, Mahidol University

Ergotamine
(migraine)
(trigger factor)
(vasodilation)






(abortive drugs)
(preventive drugs)
ergotamine
Ergotamine
Ergotamine
(serotonin)
1B 1D (5-HT1B 5-HT1D)

ergotamine -1 dopamine-2 (D2)
ergotamine (
ergotamine)
ergotamine Cafergot, Avamigran Tofago Poligot-CF
ergotamine tartrate 1 caffeine 100
Ergosia ergotamine tartrate 1

ergotamine
ergotamine

1 2

1 6

 10 ergotamine

ergotamine
Ergotamine
ergotamine
ergotamine


ergotamine
ergotamine


(rebound headache)
ergotamine
ergotamine
- : D2 (D2-receptor)
D2-receptor antagonist
domperidone
- : 1 (1-receptor)

- - (numbness): 1-receptor

- : 5-HT1B coronary

- (drug interaction): ergotamine
Cytochrome P450 3A4 (CYP 3A4)
azithromycin,
clarithromycin, ketoconazole, ritonavir verapamil
ergotamine
drug
interaction

 ergotamine
ergotamine
- ergotamine ergot alkaloid
- (peripheral arterial disease)
-
- (coronary artery disease) (angina)
-
- (sepsis)
- ()