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    Coarctation of Aorta - Patho

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    amabelles
    Coarctation of the aorta is a congenital heart defect caused by abnormal formation of the mesoderm during development resulting in an incomplete closure of the heart chambers and anomalies of the vessels. It involves a narrowing of the aorta which reduces blood flow to the lower extremities and increases blood pressure in the upper body. Symptoms include increased blood pressure in the arms, decreased pressure in the legs, fatigue, and failure to thrive in infants. Treatment options include the use of diuretics and other medications to manage symptoms or surgical repair to widen the narrowed area of the aorta.

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    Coarctation of Aorta - Patho

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    amabelles
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    Coarctation of the aorta is a congenital heart defect caused by abnormal formation of the mesoderm during development resulting in an incomplete closure of the heart chambers and anomalies of the vessels. It involves a narrowing of the aorta which reduces blood flow to the lower extremities and increases blood pressure in the upper body. Symptoms include increased blood pressure in the arms, decreased pressure in the legs, fatigue, and failure to thrive in infants. Treatment options include the use of diuretics and other medications to manage symptoms or surgical repair to widen the narrowed area of the aorta.

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    Coarctation of the aorta is a congenital heart defect caused by abnormal formation of the mesoderm during development resulting in an incomplete closure of the heart chambers and anomalies of the vessels. It involves a narrowing of the aorta which reduces blood flow to the lower extremities and increases blood pressure in the upper body. Symptoms include increased blood pressure in the arms, decreased pressure in the legs, fatigue, and failure to thrive in infants. Treatment options include the use of diuretics and other medications to manage symptoms or surgical repair to widen the narrowed area of the aorta.

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    20 views2 pages

    Coarctation of Aorta - Patho

    Uploaded by

    amabelles
    Coarctation of the aorta is a congenital heart defect caused by abnormal formation of the mesoderm during development resulting in an incomplete closure of the heart chambers and anomalies of the vessels. It involves a narrowing of the aorta which reduces blood flow to the lower extremities and increases blood pressure in the upper body. Symptoms include increased blood pressure in the arms, decreased pressure in the legs, fatigue, and failure to thrive in infants. Treatment options include the use of diuretics and other medications to manage symptoms or surgical repair to widen the narrowed area of the aorta.

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    Download as PDF, TXT or read online from Scribd
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    Coarctation of Aorta

    Predisposing Factors: >Unknown >Familial predisposition >Chromosomal anomaly > Single gene defect >Gender: Male

    Precipitating Factors: >Exposure to radiation >weak Immune defenses >exposure to intrauterine infections (rubella) >intrauterine insult >alcohol intake > Exposure to inorganic solvents >Intake of ibufprofen

    Mesoderm formation anomaly (specifically the heart)

    Incomplete closure of heart chambers

    Anomaly of the vessels

    Persistence of fetal blood vessels

    Acyanotic defects Deoxygenated blood from IVC and SVC

    Cyanotic Defects

    RA

    Tricuspid Valve

    RV

    Pulmonic Valve

    Echocardiography: Left Atrial Hypertrophy

    Pulmonary artery

    Diuretics

    Increase pressure in the pulmonary circuit

    Capillary beds of the lungs Blood Volume Pulmonary Veins LA Mitral valve

    Inc. Pressure

    Increase BP in Upper Extremities

    Pulmonary congestion

    Tachypnea Recurrent Respiratory Infection Diuretics Activation of baro receptors Stimulation of vasomotor regulatory center in the medulla LV

    Inc. Blood Volume Inc. Pressure Echocardiography: Left Ventricular Hypertrophy Interventional angiography (using a balloon catheter) Dec. Blood flow to distal vessels

    LSHF Digoxin

    Aortic Valve

    Narrowing of the aortic vessel Surgical repair

    Increase BP

    Blood vessels vasocontriction Inc. Cardiac output

    Inc. sympathoadrenal activity

    Inc. HR

    Insufficient Systemic circulation

    Dilates bronchi Decreases peristalsis and dec. gastric and salivary secretions

    Dec. tissue perfusion to the kidneys

    Inc. RR

    Decrease BP in the Lower Peripheries

    Failure to Thrive

    Dec. food absorption Poor weight gain

    RAAS Stimulation

    Vasoconstriction and sodium and water reabsorption

    Increase HR

    Increase BP

    Blood Back flow

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