Cholelithiasis Anaphysio

You might also like

Download as pptx, pdf, or txt
Download as pptx, pdf, or txt
You are on page 1of 12

Anatomy and Physiology

The Liver
Digestive function produces bile Hepatocytes secrete 8001000 of bile per day

The Gallbladder
pear-shaped sac posterior of liver 3-4 in. long stores and concentrate the bile produced by the liver (up to tenfold) releases bile into the duodenum of small intestine fat release of cholecystokinin (CCK) gallbladder contraction bile secretion

The Bile
Components: cholesterol bile salts bile pigments (e.g. bilirubin) phospholipids (e.g. lecithin) water and body salts (Na+, K+) small amounts of copper and other metals

The Bile
Yellowish brownish or olive-green liquid Can pass directly from liver into duodenum or Stored in the gallbladder (fasting state) Alkaline to neutralize the acidic chyme (pH 7.6-8.6) Function: Emulsifying agent
dietary fat fat droplets

How we degrade cholesterol


500 mg cholesterol converted to bile acid/day As bile salt and bile acid excreted in feces
Bile acid- cholic and chenodeoxycholic acid Bile salt- bile acid conjugated with taurine/glycine

Secretion in the bile transported into intestine and eliminated

SYNTHESIS OF BILE SALTS

Where does the bile go?

Liver Bile canaliculi

Bile ducts
Common hepatic duct Common bile duct Pancreatic duct Hepatopancreatic ampulla

Duodenum

References
Digestive Disorders Health Center (2010). WebMD. [Online]. Available at: http://www.cliffsnotes.com/study_guide/The-Liver-andGallbladder.topicArticleId-277792,articleId-277768.html [Accessed 11 October 2012]. The Liver and Gallbladder (n.d.) CliffsNotes. [Online]. Available at http://www.cliffsnotes.com/study_guide/TheLiver-and-Gallbladder.topicArticleId-277792,articleId277768.html [Accessed 11 October 2012]. Champe PLEASE PAKI CITE NG MAAYOS KASI EBOOK UNG AKIN. Wala sya nung front page part. Thanks (222-24)

You might also like