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  • Drug Study - Captopril

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    Glenda Galangan
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    This document summarizes information about the drug captopril, an ACE inhibitor used to treat hypertension and congestive heart failure. It works by blocking the conversion of angiotensin I to angiotensin II, lowering blood pressure. Common side effects include hypotension, rash, cough, and renal impairment. Nurses should monitor for signs of allergic reaction and angioedema, use cautiously in patients with renal or cardiac issues, and educate patients about reporting side effects and limiting activities that require alertness while taking the medication.

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    Drug Study- Captopril

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    This document summarizes information about the drug captopril, an ACE inhibitor used to treat hypertension and congestive heart failure. It works by blocking the conversion of angiotensin I to angiotensin II, lowering blood pressure. Common side effects include hypotension, rash, cough, and renal impairment. Nurses should monitor for signs of allergic reaction and angioedema, use cautiously in patients with renal or cardiac issues, and educate patients about reporting side effects and limiting activities that require alertness while taking the medication.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    1K views2 pages

    Drug Study - Captopril

    Uploaded by

    Glenda Galangan
    This document summarizes information about the drug captopril, an ACE inhibitor used to treat hypertension and congestive heart failure. It works by blocking the conversion of angiotensin I to angiotensin II, lowering blood pressure. Common side effects include hypotension, rash, cough, and renal impairment. Nurses should monitor for signs of allergic reaction and angioedema, use cautiously in patients with renal or cardiac issues, and educate patients about reporting side effects and limiting activities that require alertness while taking the medication.

    Copyright:

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    of 2

    DRUG STUDY

    MEDICATION
    captopril (Capoten)

    DRUG INDICATION / CLASSIFICATION CONTRAINDICATION


    Angiotensinconverting enzyme (ACE) inhibitor Indications: -Management of hypertension -Treatment of CHF and diabetic nephropathy Contraindications: -Hypersensitivity to captopril, other ACE inhibitors, or any component -History of angioedema

    MECHANISM OF ACTION
    Blocks ACE from converting angiotensin I to angiotensin II leading to decreased blood pressure, decreased aldosterone secretion, a small increase in serum potassium levels, and sodium and fluid loss; increased prostaglandin synthesis also may be involved in the antihypertensive action.

    DOSING & ADMINISTRATION


    tablet: 25 mg PO bid

    ADVERSE EFFECTS
    CV: Tachycardia Angina ,MI, CHF Raynaud's syndrome Hypotension in salt- or volumedepleted patients Dermatologic: Rash, pruritus Scalded mouth sensation Dermatitis Photosensitivity Alopecia GI: Gastric irritation Aphthous ulcers Peptic ulcers Cholestatic Jaundice Hepatocellular injury, Anorexia Constipation GU: Proteinuria Renal insufficiency Renal failure Polyuria,oliguria Urinary frequency Hematologic: Neutropenia Agranulocytosis Thrombocytopenia Hemolytic anemia Pancytopenia

    NURSING RESPONSIBILITIES
    Assess for history of allergy to captopril and history of angioedema. Use cautiously in patients with CHF, impaired renal function, salt or fluid volume depletion, or in pregnant or lactating women. Administer 1 hr before or Or 2 hrs. before meals. Watch out for excessive perspiration, or diarrhea; may cause hypotension Reduce dosage in patients with impaired renal function. Instruct patient to report mouth sores, fever, chills, swelling of the hands and feet, irregular heartbeat, difficulty of breathing, chest pain, swelling of the face, eyes, lips, and tongue. Instruct patient to limit activities to those that do not require alertness and precision.

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    Other: Cough, malaise dry mouth lymphadenopathy

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