NAME of DRUG Generic (Brand name)

CLASSIFICAT ION: Cephalospo rine

MECHANIS M of ACTION Secondgeneration cephalospor in that inhibits cellwall synthesis, promoting osmotic instability; usually bactericidal.

Cefuroxime Sodium

RECOMMENDE D DOSE & FREQUENCY Infusion: 750 mg, 1.5 g premixed, frozen solution Injection: 750 mg, 1.5 g

SIDE/ADVERSE EFFECTS CV: phlebitis, thrombophlebitis GI: pseudomembrano us colitis, nausea, anorexia, vomiting, diarrhea Hematologic: transient neutropenia, eosinophilia, hemolytic anemia, thrombocytopenia Skin: maculopapular and erythematous rashes, urticaria, pain, induration, sterile abscesses, temperature elevation, tissue sloughing at intramuscular injection site

CONTRAINDICATION

Stability of Drug

NSG. INTERVENTION

Dosage and Frequency:

Contraindicated in patients hypersensitive to drug. * Use cautiously in patients hypersensitive to penicillin because of possibility of crosssensitivity with other betalactam antibiotics. * Use with caution in breast-feeding women and in patients with history of colitis or renal sufficiency INDICATION Serious lower respiratory tract infections, Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenza (only strains that dont produce beta-lactamase)

Take medication as prescribed, even after feeling better. * Take oral form with food. * If suspension is being used, shake the container well before measuring dose. * Notify prescriber about rashes or superinfections. * Notify prescriber about loose stools or diarrhea.