Scribd Logo
Upload

Welcome to Scribd!

  • Laboratory Yyy Yyy Yyy

    Uploaded by

    Dalica Grace Marana
    5 views2 pages
    The document discusses the anti-streptolysin O titer (ASOT) test, which is used to determine if a person has had a recent streptococcal infection. The ASOT test checks for antibodies produced in response to streptococcal infections. A positive result may indicate a recent infection, while a negative result means no recent infection. The test is important for diagnosing potential post-streptococcal complications like rheumatic fever and glomerulonephritis. Factors like tuberculosis, microbial contamination, lipemia, and liver disease can cause false positive ASOT results. The sensitivity and specificity of the ASOT assay are important for properly managing conditions related to streptococcal infections.

    Original Description:

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    The document discusses the anti-streptolysin O titer (ASOT) test, which is used to determine if a person has had a recent streptococcal infection. The ASOT test checks for antibodies produced in response to streptococcal infections. A positive result may indicate a recent infection, while a negative result means no recent infection. The test is important for diagnosing potential post-streptococcal complications like rheumatic fever and glomerulonephritis. Factors like tuberculosis, microbial contamination, lipemia, and liver disease can cause false positive ASOT results. The sensitivity and specificity of the ASOT assay are important for properly managing conditions related to streptococcal infections.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    5 views2 pages

    Laboratory Yyy Yyy Yyy

    Uploaded by

    Dalica Grace Marana
    The document discusses the anti-streptolysin O titer (ASOT) test, which is used to determine if a person has had a recent streptococcal infection. The ASOT test checks for antibodies produced in response to streptococcal infections. A positive result may indicate a recent infection, while a negative result means no recent infection. The test is important for diagnosing potential post-streptococcal complications like rheumatic fever and glomerulonephritis. Factors like tuberculosis, microbial contamination, lipemia, and liver disease can cause false positive ASOT results. The sensitivity and specificity of the ASOT assay are important for properly managing conditions related to streptococcal infections.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    of 2

    Laboratory exercise #5 ANTI-STREPTOLYSIN O TITER I. Results /Observation Table 1.

    Result for ASOT Type of Test Qualitative Quantitative

    Result Negative: no agglutination is observed. Negative: no agglutination is observed.

    II.

    Discussion The ASO test is primarily ordered by itself or along with an anti-DNase B to help determine whether a person has had a recent streptococcal infection. In most cases, strep infections are identified and treated with antibiotics and the infections resolve. In cases where they do not cause identifiable symptoms and/or go untreated, however, post-streptococcal complications (sequelae), namely rheumatic fever and glomerulonephritis, can develop in some patients, especially young children. The test, therefore, is ordered if a person presents with symptoms suggesting rheumatic fever or glomerulonephritis and has had a recent history of sore throat or a confirmed streptococcal infection

    Guide Questions: 1. What factors may cause false positive aSOT result? Describe each. Table 2. Factors of false positive result in aSO assay Tuberculosis Microbial contamination of the serum with Bacillus and Pseudomonas, presence of these could trigger aSO antibodies react and act upon it. Lipemia This may cause non specific agglutination. Both elevated Beta-lipoprotein and cholesterol level can neutralize the ASOT. Lapsed Time Delayed readings (after 2 minutes) may cause agglutination leading to false positive result. Liver Disease Malfunction causes malabsorption of fats makes the blood specimen from which serum is obtained chylous. 2. Why time is very important in the interpretation of aSOT test? 3. How important is the sensitivity and specificity of an aSo assay for the management of rheumatic heart disease and other conditions associated with streptococcus infection?

    III.

    Conclusion

    IV.

    References Lab Test Online. Antistreptolysin O Titer. Retrieved on January 19, 2012 from http://labtestsonline.org/understanding/analytes/aso/tab/test Lee,B. Antistreptolysin O Titer. Retrieved on January 19, 2012 from http://www.scribd.com/doc/49396244/ASOT

    You might also like