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Pathology of Pneumonia
Dr. Venkatesh M. Shashidhar Senior Lecturer in Pathology Fiji School of Medicine

Introduction:
Daily

10,000 liters of air - filtered..! Pneumonia: Inflammation of lung. Respiratory tract infections commonest in medical practice. Enormous morbidity & mortality.

Etiology:
Decreased resistance - General/immune Virulent infection - Lobar pneumonia Clearing mechanism

Cough Reflex Mucosal Injury Low Alveolar defense Pulmonary edema Obstructions

Types:
Viral Bacterial Mycoplasmal Fungal

Patterns of Pulmonary infections:

Airway

- Bronchitis, Bronchiectasis Parenchyma

Pneumonia Bronchopneumonia

pneumonia Lung abscess Tuberculosis

Lobar

Bronchopneumonia

Staph, Strep, Pneumo & H. influenza Patchy consolidation not limited to lobes. Suppurative inflammation Usually bilateral Lower lobes common Complications:

Abscess Empyema Dissemination

Bronchopneumonia

Bronchopneumonia

Bronchopneumonia

Bronchopneumonia - Abscess formation

Bronchopneumonia:

Bronchopneumonia:

Bronchopneumonia - Abscess formation

Lung RSV Pneumonia:

Bronchopneumonia - CT

Bronchopneumonia - CT

Lobar Pneumonia:

Fibrinosuppurative consolidation whole lobe Rare due to antibiotic treatment. ~95% - Strep pneumoniae types 1,3,7& 2. Four stages:

Congestion. Red Hepatization. Gray Hepatizaiton. Resolution.

Lobar Pneumonia:

Lobar Pneumonia Gray hep

Lung Abscess:

Focal suppuration with necrosis of lung tissue Strep, Staph & Gram negative & anaerobes Mechanism:

Aspiration Post pneumonic Septic embolism Neoplasms

Productive Cough, fever. Clubbing Complications: Systemic spread, septicemia.

Lung Abscess:

Lung Abscess:

Lung Abscess - Chronic:

Lung Fungal Abscess: Candida

Normal Lung

Normal Lung

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