Pamantasan ng Cabuyao College of Nursing

NCM 106
Antidotes
Submitted by: Garcia, Mark Louie F. Submitted to: Mr. Herman F. Zoleta, RN, MAN

POISON/DRUG/ TOXIN
Acetaminophen/ Paracetamol Antcholinesterase Anticholinergics Benzodiazepines Beta blockers Calcium channel blockers Coumadin/Warfarin Cyanide Cyclophosphamide Digoxin Dopamine Extrapyramidal symptoms (EPS) Ethylene glycol Fluorouracil Heparin

ANTIDOTE
acetylcysteine (Mucomyst) atrophine sulfate or pralidoxime physostigmine flumazenil glucagon glucagon phytonadione (Vitamin K.) amyl nitrate, sodium nitrate, mesna digibind and digoxine immune fab phentolamie (Regitine) diphenhydramine (Benadryl) fomepizole leucoverin calcium protamine sulfate

Iron Lead Methotrexate Narcotics Neuromuscular blockade (paralytics) Opioid analgesics Tricyclic antidepressants Black widow spider Methanol Sulfonylurea hypoglycemic agents Organophospate insecticides Valproic acid Cocaine overdose Hydrogen sulfide Ethanol Mercury Insulin reaction

deferoxamine dimercapol, disodium, leucovorin calcium naloxone (Narcan) anticholinesterase agents nalmefene or naloxone phyostigmine or NaHCO3 envenomation Antivenom Folinic acid (Leucovorin) Octreotide acetate Pralidoxime chloride L-Carnitine (Carnitor) Diazepam Sodium nitrite Thiamine Succimer (Chemet) glucose (Dextrose 50%)

Cholinesterase inhibitor Morphine sulfate SALICYLATES Phenobarbital Gold CARBON MONOXIDE Caffeine Arsenic Digitalis Levenox

Pralidoxime Naloxone Hydrochloride Activated Charcoal Activated Charcoal DIMERCAPROL 100% Oxygen ESMOLOL Dimercaprol Digibing Protamin Sulfate

Black widow spider envenomation Antivenom (Latrodectus mactans) Bradydysrhythmias, cholinesterase inhibitor toxicity Atropine Acute dystonia Benztropine (Cogentin) Botulism Botulinum antitoxin / trivalent ABE Lead, copper, zinc, cobalt, cadmium toxicity Calcium disodium EDTA (Versenate) Hydrofluoric acid exposure, calcium channel blocker toxicity Calcium gluconate 10% Crotalinae (rattlesnake) envenomation Crotalinae polyvalent immune FAB (CroFab) Serotonin syndrome Cyproheptadine (Periactin) Malignant hyperthermia, neuroleptic malignant syndrome Dantrolene (Dantrium) Deferoxamine mesylate (Desferal) Iron toxicity Diazepam / lorazepam (Valium / Ativan) Seizures, severe agitation; stimulant toxicity Digoxin-specific antibody fragments (Digifab, Digibind) Digoxin and other cardiac glycoside toxicity Dimercaprol / BAL Arsenic, lead, mercury toxicity Diphenhydramine (Benadryl) Acute dystonia; histamine receptor blockade Flumazenil (Romazicon) Benzodiazepine toxicity Folic acid (Folvite) Methanol toxicity Fomepizole (Antizol) Ethylene glycol, methanol toxicity Glucagon Beta-blocker, calcium channel blocker toxicity Hydroxocobalamin (Cyanokit) Cyanide exposure / smoke inhalation Leucovorin calcium Methotrexate toxicity Levocarnitine (Carnitor) Valproic acid toxicity Levoleucovorin calcium Methotrexate toxicity Methylene blue 1% Methemoglobinemia Naloxone (Narcan) Opioid toxicity Octreotide (Sandostatin) Sulfonylurea toxicity Physostigmine (Antilirium) Anticholinergic toxicity Phytonadione / Vitamin K1 (AquaMEPHYTON / Mephyton) Oral anticoagulant / rodenticide toxicicty Pralidoxime / 2-PAM (Protopam) Cholinesterase inhibitor (organophosphate / carbamate) toxicity Protamine Heparin reversal Pyridoxine / Vitamin B6 Ethylene glycol / isoniazid / Gyromitra mushroom toxicity Sodium bicarbonate Cyclic antidepressant / salicylate toxicity, metabolic acidosis Succimer / DMSA (Chemet) Arsenic, lead, mercury Thiamine / Vitamin B1 Wernicke-Korsakoff syndrome, ethylene glycol toxicity