Scribd Logo
Upload

Welcome to Scribd!

  • Epithelial Dysplasia

    Uploaded by

    Roja Lakshmi
    12 views16 pages
    This document discusses epithelial dysplasia, including its definition, the mechanisms behind its transformation from normal to dysplastic tissue, and methods for grading epithelial dysplasia. It lists cellular changes like abnormal nuclear size and shape, increased nuclear-cytoplasmic ratio, and architectural changes like loss of cell cohesion and irregular stratification. Methods for grading dysplasia as mild, moderate, severe or carcinoma in situ are also presented.

    Original Description:

    Original Title

    1280464_634595190983403750

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    PPTX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    This document discusses epithelial dysplasia, including its definition, the mechanisms behind its transformation from normal to dysplastic tissue, and methods for grading epithelial dysplasia. It lists cellular changes like abnormal nuclear size and shape, increased nuclear-cytoplasmic ratio, and architectural changes like loss of cell cohesion and irregular stratification. Methods for grading dysplasia as mild, moderate, severe or carcinoma in situ are also presented.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    12 views16 pages

    Epithelial Dysplasia

    Uploaded by

    Roja Lakshmi
    This document discusses epithelial dysplasia, including its definition, the mechanisms behind its transformation from normal to dysplastic tissue, and methods for grading epithelial dysplasia. It lists cellular changes like abnormal nuclear size and shape, increased nuclear-cytoplasmic ratio, and architectural changes like loss of cell cohesion and irregular stratification. Methods for grading dysplasia as mild, moderate, severe or carcinoma in situ are also presented.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    of 16

    EPITHELIAL DYSPLASIA

    Defination of epithelial dysplasia Dyplasia-Reagon 1958

    MECHANISM OF TRANSFORMATION OF EPITHELIUM FROM NORMAL TO DYSPLASTIC CHANGES

    GRADING OF EPITHELIAL DYSPLASIA AND ITS APPLICATIONS:


    1. Smith and Pindborgsphotographic method (1969) 2. Banoczy and Csiba (1976) 3. WHO (1978) 4. Kramer (1980) 5. Burkhardt and Maerkar (1981) 6. Lumermann H Et al (1995) 7. Neville et al (1995) 8. Speight P M et al (1996) 9. Kuffer and Lombardi (2002) 10. Ljubljana (2003) 11. Brothwell DJ (2003) 12. Binary system (2005)

    CELLULAR CHANGES
    Abnormal variation in nuclear size and shape Abnormal variation in cell size and shape Increased nuclear/cytoplasm Enlarged nuclei and cell Hyperchromatism Increased mitotic figures Increased number and size of nucleoli

    ARCHITECTURAL CHANGES
    Loss of cohesion Basal cell hyperplasia Dyskeratosis Bulbous rete pegs Irregular epithelial stratification Keratin pearl within rete pegs Acanthosis

    GRADING OF DYSPLASIA
    Mild Moderate Severe Carcinoma in situ

    You might also like