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COPD

ASTHMA

CHRONIC BRONCHITIS

EMPHYSEMA

Allergens (dust, pollens, molds Cigarettes, smoke,etc.)

H. influenza Diplococcus Pneumoniae

Cigarette Smoking

Anti alpha antitrypsin D.

Inflammation of the Bronchi Activates Ige Bradykinin, Histamine, Prostaglandin

Breakdowns of elastin

destruction of alveolar wall septa

Mast cells & Basophils Release Histamine, Leukotrienes, Prostaglandin, Cytokines, Serotonin

Inc. capillary Permeability


Inc. Dead space Dec.pulmonary bed

Fluid/ Cell Exudation Inc. CO2 Edema of mucous membrane Inc.blood flow

Inflammation of bronchial airway Inc. activity of Goblet Cells Vasodilation Hypersecretion of mucous

hypercapnea

Inc. RBC

additional expansion of the thorax

Bronchoconstriction

Plugged airway

pinkish Barrel chest

wheezes

Dec. intrathoracic pressure

Dec. O2 lungs

Persisted Cough

hypoxia

Decreased Oxygen Blood circulation

cyanosis

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