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    The document contains questions that may appear on a Computational Molecular Biology exam. It includes questions about: 1) The role of computational molecular biology in elucidating genome information and definitions of dynamic programming and single nucleotide polymorphism. 2) How gene expression studies are carried out using cDNA microarrays. 3) Definitions of Ramachandran plot and protein threading. 4) The steps involved in the Fitch–Margoliasch algorithm and phylogenetic trees. 5) The concept of homology modeling in predicting three-dimensional protein structure. 6) The application of bioinformatics tools in drug discovery and drug designing. 7) Definitions of gene prediction methods and the Chou fasman

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    The document contains questions that may appear on a Computational Molecular Biology exam. It includes questions about: 1) The role of computational molecular biology in elucidating genome information and definitions of dynamic programming and single nucleotide polymorphism. 2) How gene expression studies are carried out using cDNA microarrays. 3) Definitions of Ramachandran plot and protein threading. 4) The steps involved in the Fitch–Margoliasch algorithm and phylogenetic trees. 5) The concept of homology modeling in predicting three-dimensional protein structure. 6) The application of bioinformatics tools in drug discovery and drug designing. 7) Definitions of gene prediction methods and the Chou fasman

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    18 views1 page

    R7322301 Computational Molecular Biology

    Uploaded by

    sivabharathamurthy
    The document contains questions that may appear on a Computational Molecular Biology exam. It includes questions about: 1) The role of computational molecular biology in elucidating genome information and definitions of dynamic programming and single nucleotide polymorphism. 2) How gene expression studies are carried out using cDNA microarrays. 3) Definitions of Ramachandran plot and protein threading. 4) The steps involved in the Fitch–Margoliasch algorithm and phylogenetic trees. 5) The concept of homology modeling in predicting three-dimensional protein structure. 6) The application of bioinformatics tools in drug discovery and drug designing. 7) Definitions of gene prediction methods and the Chou fasman

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    Code: R7322301

    R07

    III B. Tech II Semester (R07) Supplementary Examinations, April/May 2013 COMPUTATIONAL MOLECULAR BIOLOGY (Biotechnology) Time: 3 hours Max. Marks: 80 Answer any FIVE questions All questions carry equal marks ***** 1 What is functional genomics? Discuss the role of computational molecular biology in elucidating the genome information. Write short notes on: (a) Dynamic programming. (b) Single nucleotide polymorphism. What are micro arrays? Explain how gene expression studies are carried out using cDNA micro arrays. Write short notes on: (a) Ramachandran plot. (b) Protein threading. What is a phylogenetic tree? Discuss briefly the steps involved in Fitch Margoliasch algorithm. Explain the concept of homology modeling in prediction of three dimensional structure of protein. What is drug designing? Explain the application of various bioinformatics tools in drug discovery process. Write short notes on: (a) Gene prediction methods. (b) Chou fasman method.

    5 6 7

    *****

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