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    The document introduces substance use disorders (SUDs) and provides diagnostic criteria for abuse and dependence. It notes abuse involves a maladaptive pattern of substance use leading to impairment or distress, as defined by one or more criteria within a 12-month period. Dependence is more severe, involves overcoming normal judgment, and requires meeting three or more criteria within 12 months. Additionally, it briefly mentions the gene-environment effects on SUDs pathogenesis, including factors like low socioeconomic status and drug availability, as well as the neuronal pathways involved, such as drugs of abuse increasing dopamine concentrations in the nucleus accumbens reward center.

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    neuro medical school

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    Introduction to Substance Use Disorders

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    The document introduces substance use disorders (SUDs) and provides diagnostic criteria for abuse and dependence. It notes abuse involves a maladaptive pattern of substance use leading to impairment or distress, as defined by one or more criteria within a 12-month period. Dependence is more severe, involves overcoming normal judgment, and requires meeting three or more criteria within 12 months. Additionally, it briefly mentions the gene-environment effects on SUDs pathogenesis, including factors like low socioeconomic status and drug availability, as well as the neuronal pathways involved, such as drugs of abuse increasing dopamine concentrations in the nucleus accumbens reward center.

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    9 views2 pages

    Introduction To Substance Use Disorders

    Uploaded by

    kep1313
    The document introduces substance use disorders (SUDs) and provides diagnostic criteria for abuse and dependence. It notes abuse involves a maladaptive pattern of substance use leading to impairment or distress, as defined by one or more criteria within a 12-month period. Dependence is more severe, involves overcoming normal judgment, and requires meeting three or more criteria within 12 months. Additionally, it briefly mentions the gene-environment effects on SUDs pathogenesis, including factors like low socioeconomic status and drug availability, as well as the neuronal pathways involved, such as drugs of abuse increasing dopamine concentrations in the nucleus accumbens reward center.

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    Introduction to Substance Use Disorders (SUD) April 14, 2010 1.

    List the SUDs and describe the diagnostic criteria for each Disorder
    Abuse

    Definition
    Maladaptive pattern of substance use leading to clinically significant impairment or distress, as manifested by 1+ of the criteria w/in 12mo period

    Criteria
    Recurrent substance use resulting in failure to fulfill major role obligations @ work, school, home, etc Recurrent use in situations in which it is physically hazardous (e.g. driving) Recurrent drug-related legal problems (e.g. getting arrested) continued use despite having persistent social/interpersonal problems worsened by the substance (e.g. fights w/ spouse about consequences of drug) Tolerance: need for markedly amts of substance to get same effect diminished effect w/ continued use of the same amount of the substance Withdrawal: withdrawal syndrome same substance is used to relieve or avoid w/d sxs Substance is taken in amounts or over longer period than was intended Persistent desire/unsuccessful efforts to cut down or control substance use Spend a lot of time trying to obtain drug Important activities are given up or reduced because of use Substance use is continued despite having psych/physio problem caused by use

    Dependen ce

    More severe in intensity and has overcome the normal process of judgement and decision making LIFE EVOLVES AROUND THE USE need 3+ of the criteria w/in 12mo period

    2. Explain the gene-environment effect on the pathogenesis of SUDs a. Environment: low SES, poor parental support, drug availability

    3. Describe the neuronal pathways involved in the pathogenesis of SUDs a. Dopamine system i. Drugs of abuse increase extracellular DA concentrations in limbic regions, including the nucleus accumbens (reward/pleasure)

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