Graves Disease: You treat it with Methimazole, which inhibits Thyroperoxidase. So you get less T3 and T4 in the plasma.

However, you still have stimulating antibodies and eventually, TSH levels will rise because of the decreases in T3 and T4. So, what is the fate of the goiter? The thyroid tissue is still being stimulated. TSH and antibodies will continue to drive hypertrophy, increase blood supply, etc. Is is that Methimazole has possible immunosuppressant effects? Referred Pain: Is there any kind of correlation between the location of infarcted myocardium and the pattern of referred pain?