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  • Roll No. Total No. of Questions: 101 (Total No. of Pages: 02

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    Sharn Gill
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    This document contains instructions for a 101 question exam divided into 3 sections. Section A contains 15 compulsory questions asking about the chemical structures, uses and definitions of various drugs. Section B contains 4 out of 6 optional questions about drug SAR, receptor types, synthesis methods, and how isomerism affects activity. Section C contains 3 out of 10 optional long-form questions about drug classes, synthesis methods, receptor antagonists, physicochemical parameters, and bioisosterism.

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    3.6.1 dec 09

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    This document contains instructions for a 101 question exam divided into 3 sections. Section A contains 15 compulsory questions asking about the chemical structures, uses and definitions of various drugs. Section B contains 4 out of 6 optional questions about drug SAR, receptor types, synthesis methods, and how isomerism affects activity. Section C contains 3 out of 10 optional long-form questions about drug classes, synthesis methods, receptor antagonists, physicochemical parameters, and bioisosterism.

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    6 views2 pages

    Roll No. Total No. of Questions: 101 (Total No. of Pages: 02

    Uploaded by

    Sharn Gill
    This document contains instructions for a 101 question exam divided into 3 sections. Section A contains 15 compulsory questions asking about the chemical structures, uses and definitions of various drugs. Section B contains 4 out of 6 optional questions about drug SAR, receptor types, synthesis methods, and how isomerism affects activity. Section C contains 3 out of 10 optional long-form questions about drug classes, synthesis methods, receptor antagonists, physicochemical parameters, and bioisosterism.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    of 2

    Roll No. Total No.

    of Questions: 101

    &q\r409
    [Total No. of Pages: 02

    Time : 03 Hours Instruction to Candidates: 1) Section- A is ComPulsorY. 2) 3) from Section- B. Attempt any Four questions Attempt any Three questionsfrom Section- C. Section - A gl)

    (15x 2 :30)

    ")

    Give the chemicalstructureand usesof the following drugs : D ii) iii) lv) v) vi) vii) viii) ix) x) Diphenhydramine. Promethazine. Cyproheptadine. Famotidine. Naproxen. Allopurinol. Tblmetin. Omeprazole. sodium. Diclotbnac Propranolol.

    b) Define the foliowings : xi) xiD xiii) xiv) xv) Prostaglandins. isomerism. Geermetrical Taft's steric factor. Molar refractivity parameterLeadeiPtimization.

    J-e8[8I2el

    14..1:o.

    Section- B (4r5=20) Hanschmultiparameter modelof QSAR analysis. Q2) Describe drugsgive their SAR? Q3) What are adrenergic and uses of : Q4) Give the methodof synthesis (a) Propranolol. (b) Indomethacin. affectsthe biologicalactivity? QS) Explain how opticalisomerism Q6) Write a.noteon C.A.D.D.

    section-c (3*ro:30)
    give the method Classifythemwith example, Q7) Whatareanalgesic-antipyretics, of preparation of flufenamicacid and analgin. give synthesis of chlorpheniramine and Q8) What are H, receptorantagonists, give SAR of phenothiazines. Q9) Write a note on : (a) Lipophilic parameter. (b) Electronic parameter. write a detailaccount with examples. QI0) (a) Define Bioisosterism, (b) Write a accountof antiulcerdrugs.

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    J-98

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