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Disruption Of The Normal Regular Ovulation & Presented To The Clinicians With A Very Wide Range Of Symptoms & Signs

Incidental Finding - Asymptomatic- Regular Cycle No Hormonal Disturbance

USG: 10 ++ cysts per ovary, 2-8 mm in diameter surrounding an echo-dense stroma.

Weight Gain (Obesity) -High Serum Leptin

BMI > 30 kgs /m2 ( High Risk ) Greater Frequency of Hyperinsulinaemia

Primary or secondary amenorrhea

Irregular menstrual cycles And Oligo menorrhea

Infertility

High Level Leutinizing Hormone

Hyperandrogenism and hirsutism

High Level Of androgen

Recurrent abortions

Acne vulgaris

 Increased androgens Increased LH Increased Fasting insulin Increased Prolactin Increased estradiol, estrone Decreased sex hormone binding globulin

 Vaginal USG : 100 % Success Abdominal USG : 30% Failure

 Obesity To Weight reduction Metformin tablets To inhibit hepatic glucose and decrease insulin low-calorie diet for females with BMI >30kg/m2 & truncal obesity.

 Low-dose combined oral contraceptive preparations Result in artificial non-ovulatory cycles and regular shedding of the endometrium

Progesterone: Medroxyprogesterone acetate or dydrogesterone for five days every one to three months

Infertility
Ovulation can be induced by antiestrogenes, clomiphene citrate (5-100 mg) or tamoxifen 20-40% mg on days two through six of natural or induced bleeding. In resistant cases, we can use parenteral gonadotrophin therapy with very careful continuous monitoring of the ovaries, or we can use laparoscopic diathermy.

Hyperandrogenism and hirsutism

Treatment options include medical and cosmetic therapies. To stop further progression of hirsutism and decrease the hair growth rate, Will take at least six to nine months before any benefit is perceived. Physical treatment: waxing, bleaching, electrolysis, and laser therapy,

Laparoscopic Diathermy

Wedge Resection

Diabetes Mellitus

Dyslipidaemia

Hypertension

Endometrial carcinoma .