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Key Topics to learn

Respiratory

Oxygen cascade Closing capacity Compliance and P-V curve for lung and chest walls Dead space (inc. vol vs capacity) FRC and significance O2 transport O2 dissociation curve (O2, hemoglobin, myoglobin, cardiac output, 2,3DPG, sats) CO2 transport difference between top and bottom @ normal and low volume Volume, pressure and flow during normal breathing Preoxygenation and O2 store Hypoxemia vs hypoxia ?Pneumothorax Flow-volume loop Surfactant non-respiratory functions of the lung Effects of high altitude, diving RBC and function (include pH, O2, CO2) Mechanics of breathing A-a gradient - neonate vs adult, effects of shunt and V/Q mismatch on pO2 and pCO2

Fluid

Water balance (thirst, ADH, etc) Lymph CSF Tonicity Osmolarity/osmolality

Notes on lymph, CSF,

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