Professional Documents
Culture Documents
Codeine Phosphate Oral Solution - bp2009
Codeine Phosphate Oral Solution - bp2009
General Notices
Action and use Opioid receptor agonist; analgesic. DEFINITION Codeine Phosphate Oral Solution is a solution containing 0.5% w/v of Codeine Phosphate or an equivalent concentration of Codeine Phosphate Sesquihydrate in a suitable flavoured vehicle. Extemporaneous preparation The following formula and directions apply.
Codeine Phosphate 5g
Water 15 ml
Chloroform Spirit 25 ml
Dissolve the Codeine Phosphate in the Water, add 750 ml of the Syrup and mix. Add the Chloroform Spirit and sufficient of the Syrup to produce 1000 ml and mix. It should be recently prepared. The oral solution complies with the requirements stated under Oral Liquids and with the following requirements. Content of codeine phosphate C18H21NO3,H3PO4, H2O 0.475 to 0.525% w/v. IDENTIFICATION Related substances Complies with the requirements stated under Codeine Linctus. ASSAY
Carry out the Assay described under Codeine Linctus. STORAGE Codeine Phosphate Oral Solution should be protected from light.