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ENDOCRINE SYSTEM

Prepared by: MSYasay, RPh, (MPH), MD

consists of glands and tissues that secrete hormones

ENDOCRINE SYSTEM

HORMONES
chemical signals that affect the behavior of other glands or tissues influence the metabolism of cells, the growth and development of body parts, and homeostasis

ENDOCRINE GLANDS
secrete their hormones directly into tissue fluid.

EXOCRINE GLANDS
have ducts and secrete their products into these ducts

EXOCRINE vs. ENDOCRINE

TYPES OF HORMONES
Peptide

PEPTIDE HORMONES
change in cellular behavior formation of an end product that leaves the cell

TYPES OF HORMONES
Steroid

HORMONE CONTROL
(1) the concentration of dissolved molecules or ions in the blood (2) by the actions of other hormones; and/or (3) by the nervous system

ENDOCRINE AND NERVOUS


the brain can make appropriate adjustments to ensure homeostasis while you eat a meal sensory information is relayed to the brain brain parasympathetic neurons release insulin from the pancreas

HYPOTHALAMUS AND PITUITARY

EFFECTS OF HORMONES
Hormones that affect other glands TSH ACTH Gonadotropic hormones FSH LH

EFFECTS OF HORMONES
Prolactin (PRL) causes the mammary glands in the breasts to develop and produce milk

EFFECTS OF HORMONES
Growth Hormone (GH)
aka somatotropic hormone stimulates protein synthesis within cartilage, bone, and muscle. It stimulates protein synthesis promotes fat metabolism increases glycolysis

PATHOLOGY: DWARFISM

GIGANTISM

GIGANTISM

ACROMEGALY

Thyroid Glands

THYROID AND PARATHYROID

large gland located in the neck attached to the trachea just below the larynx

Thyroid Glands composed of a large number of follicles each a small spherical structure made of thyroid cells filled with T3 TRI IODOTHYRONINE T4 THYROXINE

THYROID AND PARATHYROID

EFFECTS OF THYROID HORMONES


METABOLISM OF THE CELLS No ONE target organ

EFFECTS OF THYROID HORMONES

EFFECTS OF THYROID HORMONES

NORMAL

Endemic Goiter vs Exophthalmic Goiter

PATHOLOGY

PARATHYROID GLANDS
Calcitonin: maintains Calcium in the body Calcium plays a significant role in nervous conduction muscle contraction Coagulation (clotting) of blood.

PARATHYROID GLANDS

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