Because of the hydrophobic core the membrane bilayers are virtually impermeable to salts , sugars and most small

hydrophilic moelcules. The hydrophobic core makes it impermeable for difussion of to water & water soluble solutes across the membrane. The lipid bilayers are highly stable because of their hydrophobic interactions and van der waals interactions. The phospholipids can spontaneously form sealed closed compartments.

Each phospholipid molecule consists of an enlarged head and two tails. Head end: polar end The head end is soluble in water and is said to be hydrophilic. The tail end : non-polar end The tail end is insoluble in water and is said to be hydrophobic.

Cholesterol
It is an important component of mammalian cell membrane and is essential for proper membrane permeability and fluidity.