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CONDITIONS THAT CAUSE AZOOSPERMIA

Pr im ar y test icul ar f ail ure


Klinefelter syndrome
Y chromosome microdeletions
Genetic infertility due to abnormal chromosomes (karyotype)
Unexplained genetic infertility

Secondary t est icular fail ur e


Kallman Syndrome
Unexplained gonadotropin deficiency
Hypothalamic/pituitary tumor
Hyperprolactinemia
Cancer treatment (chemotherapy, radiation, surgery)
Varicocele effec

P it uit ar y suppress ion


Drug induced (anabolic steroids, alcohol, glucocorticoids)
Testosterone supplements
Congenital adrenal hyperplasia
Severe illness (cancer, kidney or liver failure)
Diabetes mellitus
Sickle cell anemia
Hemachromatosis

Sper m aut oim m unit y

Pest icid e/t oxin exp os ure (incl ud ing hot t ubs and
b at hs)

U ndes ce nd ed t est icles at b irt h

O bst r uct ion


Congenital absence of the vas deferens (CAVD)
Ejaculatory duct obstruction
Epididymitis
Scrotral trauma or surgery
Young syndrome
Vasectomy

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