Loa Loa: The African"eye Worm"

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Loa loa

The Africaneye worm

Geographical distribution Also called Loaiasis or Loiasis West and Central parts of Africa

The vector is a day-time biting fly

Chrysops silacea

Calabar swelling
On hands, wrists, forearms or other sites. Painless, non-pitting.

Last from few hours to several days.


May recur for years. Due to hosts immune response to the parasites antigen. Generalized pruritis, fatigue and arthralgia are common.

Serious complications:
Microfilariae invade CNS, heart, Kidneys or other vital organs.

Adults live in the subcutaneous tissue of man.

Under the conjunctiva of the eye.

Loa loa adult in Calabar swelling x section

Diagnosis Clinical: worms under the skin or conjunctiva. Laboratory: - Microfilariae in blood (at day time). - Serology. - PCR. - Eosinophilia.

Treatment: Chemotherapy as in Bancroftian filariasis. Surgical removal of adults.

Prevention & control:


Treatment of patients. Vector control.

Summary
Parasite W. bancrofti B. malayi B. timori O. volvulus L. loa M. perstans M. streptocerca M. ozzardi
8/22/2013

Mosquito Culex Mansonia Anopheles/Mansonia Simulium flies Chrysops flies Culicoides Culicoides Culicoides

Disease LF LF LF River Blindness S/c swellings Serous cavity


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