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    University of Immaculate Conception (CRF)

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    Jellou Mac
    Chronic renal failure can be caused by both modifiable and non-modifiable predisposing factors such as family history of diabetes or hypertension, lifestyle factors like smoking, certain diseases like diabetes or glomerulonephritis, and age over 55. As kidney function deteriorates, the remaining nephrons hypertrophy but cannot compensate for the loss of function, leading to a loss of excretory functions and complications like anemia, metabolic acidosis, hyperphosphatemia, and eventually uremia.

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    University of Immaculate Conception (CRF)

    Uploaded by

    Jellou Mac
    16 views2 pages
    Chronic renal failure can be caused by both modifiable and non-modifiable predisposing factors such as family history of diabetes or hypertension, lifestyle factors like smoking, certain diseases like diabetes or glomerulonephritis, and age over 55. As kidney function deteriorates, the remaining nephrons hypertrophy but cannot compensate for the loss of function, leading to a loss of excretory functions and complications like anemia, metabolic acidosis, hyperphosphatemia, and eventually uremia.

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    Chronic Renal Failure

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    Chronic renal failure can be caused by both modifiable and non-modifiable predisposing factors such as family history of diabetes or hypertension, lifestyle factors like smoking, certain diseases like diabetes or glomerulonephritis, and age over 55. As kidney function deteriorates, the remaining nephrons hypertrophy but cannot compensate for the loss of function, leading to a loss of excretory functions and complications like anemia, metabolic acidosis, hyperphosphatemia, and eventually uremia.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
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    Download as doc, pdf, or txt
    16 views2 pages

    University of Immaculate Conception (CRF)

    Uploaded by

    Jellou Mac
    Chronic renal failure can be caused by both modifiable and non-modifiable predisposing factors such as family history of diabetes or hypertension, lifestyle factors like smoking, certain diseases like diabetes or glomerulonephritis, and age over 55. As kidney function deteriorates, the remaining nephrons hypertrophy but cannot compensate for the loss of function, leading to a loss of excretory functions and complications like anemia, metabolic acidosis, hyperphosphatemia, and eventually uremia.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as doc, pdf, or txt
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    University of Immaculate Conception

    Davao city

    CHRONIC RENAL FAILURE


    Schematic diagram

    PREDISPOSING FACTORs:
    * family history (DM,HPN) Deterioration and destruction of nephrons Decreased GFR and clearance (serum creatinine and BUN increases) modifiable factors: factors Lifestyle (smoking, alcohol) * Certain diseases (DM, CGN) non modifiable * age 55 years old and above *

    Remaining functioning nephrons hypertrophy (Dilute urine , polyuria) ( hyponatremia) Further loss of kidney function loss of excretory renal function loss of non-excretory renal function Kidney losses ability to concentrate urine loss of Na

    H secretion and HCO3 phosphate excretion failure in the production of erythropoietiin reabsorption metabolic acidosis infection hyperphosphatemia anemia calcium reabsorption

    K excretion

    NA reabsorption in renal tubules

    excretion of nitrogenous waste uremia

    immune disturbance

    hyperkalemia

    water retention

    delayed wound healing

    pallor

    HPN

    edema

    (tetany, muscle spasms, arrhythmias)

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