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University of Immaculate Conception (CRF)
University of Immaculate Conception (CRF)
Davao city
PREDISPOSING FACTORs:
* family history (DM,HPN) Deterioration and destruction of nephrons Decreased GFR and clearance (serum creatinine and BUN increases) modifiable factors: factors Lifestyle (smoking, alcohol) * Certain diseases (DM, CGN) non modifiable * age 55 years old and above *
Remaining functioning nephrons hypertrophy (Dilute urine , polyuria) ( hyponatremia) Further loss of kidney function loss of excretory renal function loss of non-excretory renal function Kidney losses ability to concentrate urine loss of Na
H secretion and HCO3 phosphate excretion failure in the production of erythropoietiin reabsorption metabolic acidosis infection hyperphosphatemia anemia calcium reabsorption
K excretion
immune disturbance
hyperkalemia
water retention
pallor
HPN
edema