Scribd Logo
Upload

Welcome to Scribd!

  • 10 views

    5-Carbapenems and Monobactams - 090ct2012

    Uploaded by

    Idrissou Fmsb
    Carbapenems like imipenem, meropenem, and ertapenem have the broadest spectrum of antimicrobial activity and are used to treat hospital-acquired infections like respiratory tract infections, septicemia, intraabdominal infections, and bone and joint infections. Monobactams like aztreonam primarily target gram-negative aerobes and are used to treat urinary tract infections, respiratory infections, meningitis, and other infections caused by susceptible gram-negatives, especially in penicillin-allergic patients requiring gram-negative coverage.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content

    You might also like

    5-Carbapenems and Monobactams - 090ct2012

    Uploaded by

    Idrissou Fmsb
    10 views5 pages
    Carbapenems like imipenem, meropenem, and ertapenem have the broadest spectrum of antimicrobial activity and are used to treat hospital-acquired infections like respiratory tract infections, septicemia, intraabdominal infections, and bone and joint infections. Monobactams like aztreonam primarily target gram-negative aerobes and are used to treat urinary tract infections, respiratory infections, meningitis, and other infections caused by susceptible gram-negatives, especially in penicillin-allergic patients requiring gram-negative coverage.

    Original Description:

    Original Title

    5-Carbapenems and Monobactams- 090ct2012

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    PPT, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Carbapenems like imipenem, meropenem, and ertapenem have the broadest spectrum of antimicrobial activity and are used to treat hospital-acquired infections like respiratory tract infections, septicemia, intraabdominal infections, and bone and joint infections. Monobactams like aztreonam primarily target gram-negative aerobes and are used to treat urinary tract infections, respiratory infections, meningitis, and other infections caused by susceptible gram-negatives, especially in penicillin-allergic patients requiring gram-negative coverage.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as ppt, pdf, or txt
    10 views5 pages

    5-Carbapenems and Monobactams - 090ct2012

    Uploaded by

    Idrissou Fmsb
    Carbapenems like imipenem, meropenem, and ertapenem have the broadest spectrum of antimicrobial activity and are used to treat hospital-acquired infections like respiratory tract infections, septicemia, intraabdominal infections, and bone and joint infections. Monobactams like aztreonam primarily target gram-negative aerobes and are used to treat urinary tract infections, respiratory infections, meningitis, and other infections caused by susceptible gram-negatives, especially in penicillin-allergic patients requiring gram-negative coverage.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as ppt, pdf, or txt
    of 5

    Carbapenems and Monobactams

    Pharmacology L3 PHCL-L3-AntiMicro-

    Carbapenems
    Imipenem, Meropenem, and Ertapenem

    Most broad spectrum of activity of all antimicrobials Have activity against gram-positive and gram-negative aerobes and anaerobes Bacteria not covered by carbapenems include MRSA, coagulase-negative staph, C. difficile, Nocardia

    Monobactams
    Spectrum of Activity

    Aztreonam bind preferentially to PBP 3 of gram-negative aerobes; has little to no activity against gram-positives or anaerobes Gram-negative

    E. coli, K. pneumoniae, P. mirabilis, H. influenzae, M. catarrhalis, Enterobacter, Citrobacter, Providencia, Salmonella, Shigella and Pseudomonas aeruginosa
    3

    Carbapenems
    Clinical Uses

    Hospital acquired infections such as:


    respiratory tract infections, septicemia, intraabdominal infections, skin and soft tissue infections, bone and joint infections (not ertapenem if Pseudo)

    Polymicrobial infections Empiric therapy


    Febrile neutropenia imip and mero Meningitis - meropenem


    4

    Monobactams
    Clinical Uses

    Urinary tract infections, respiratory tract infections, meningitis, bacteremia, skin and soft tissue infections, and intraabdominal infections caused by susceptible gram-negatives Penicillin-allergic patients who require antibiotic with gram-negative coverage

    You might also like