ABO lood Groups B

Blood Type RBC

Ag

Plasma/Serum
Ab

AntiA (-) Agg (+) Agg (+) Agg

Anti-B

A B AB O

A B

Anti-B Anti-A A&B NONE

(+)Agg (-) Agg

(+) Agg

NONE

Anti-A & Anti-B

(-) Agg

(-) Agg

 Possible blood type

Mom AO AO=A AB=AB BO= B OO=O AO Dad BO

AB

BO

OO

Rh BLOOD GROUP
Very important blood group 1st studied on rhesus monkeys Rh+ with D antigen on RBC surface Rh- without the D antigen Rh antibodies against Rh antigens do not develop unless Rh- person is exposed to Rh+ RBC

 HDN- Hemolytic Disease of The New Born

Erythroblastosis fetalis Occur by blood transfusion or via transplacental from fetus to mother. TRANSFUSION Rh negative transfused with Rh positive= sensitized to the Rh antigens thus produce anti-Rh antibodies. 2nd transfusion= transfusion reaction can occur.

 Pregnancy- First baby Mother- Rh negative > 80% baby is Father- Rh positive > Rh + Mother anti-D Second baby > HDN Rh+ : anti-D (M) react with babys blood

 HDN- 1st aid- transfusion to replace babys blood via umbilical cord transfusion or delivery when baby is mature. Prev- Mom- given specific type of Ab preparation (injection)= Rho (D) immunoglobulin called RhoGAM