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Osteosarcoma
Osteosarcoma
What is Osteosarcoma?
The most common primary malignant neoplasm of bone that occurs in children and young adults
Pathophysiology
1. 2. 3. 4. 5. 6. Osteoblast DNA mutation Malignant osteoblast (abnormal) Proliferation of abnormal osteoblast Formation of osteoid or immature bone Signs and symptoms are then observed such as pain, swelling, and tenderness.
Risk Factors:
Children Teenage growth spurt Tall for the age Previous treatment with radiation Benign and non-cancerous bone tumors Retinoblastoma Adult High fat diet Lack of exercise Smoking Drinking alcohol
Non-specific symptoms like fever, unintentional weight loss, fatigue, and anemia can also be symptoms of osteosarcoma. But they are also indicators of other less severe conditions.
Prognosis
The prognosis for patients diagnosed with Osteosarcoma depends primarily on whether metastases are detectable at diagnosis. Patients who present with metastases have a very poor prognosis, with long-term survival rates of less than 25%. For patients with initially localized disease, the prognosis depends mainly on 2 variables: resectability and response to chemotherapy. Those who have completely resectable disease and those whose tumors have an excellent histologic response to neoadjuvant chemotherapy have the best chance for cure.
Osteosarcoma
Codman triangle is a term used to describe the triangular area of new subperiosteal bone that is created when a lesion, often a tumour, raises the periosteum away from the bone. sun-burst" appearance on X-ray examination due to the tumor spicules of calcified bone radiating in right angles
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Codman triangle
Codman triangle
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Osteosarcoma
Codman's triangle
Osteosarcoma
NURSING MANAGEMENT
Provide quiet environment and calm activities to prevent or lessen pain. Provide comfort measure such as back rub, change position and use of heat or cold application. Encourage diversional activities Administer analgesics as indicated to maximal dose as needed. Encourage the patient to increase fluid intake. Encourage rest periods to prevent fatigue. Provide accurate information about the situation, medication and treatment. Assess muscle strength, gross and fine motor coordination. Provide pillows for cushion and support. Keep side rails up all the time.