Vn c cht 3-MCPD trong thc phm

Written by Le Tien Dung Wednesday, 27 June 2007 03:22

3-MCPD l mt cht thuc nhm chloropropanols c tn ho hc l 3-monochloro propane 1,2diol. Cht Triglyceride (C3H5(OH)3) trong cht bo khi tc dng v axit chlohydric (HCl) th to thnh 3-MCPD v 3 dn xut khc (1,3-DCP; 2,3-DCP; v 2-MCPD). 3-MCPD c to thnh do s phn ng gia cht Clo v cht bo trong qu trnh ch bin thc phm. Phn ng c thc y nhanh hn khi xy ra nhit cao (gia nhit). 1Cht 3-MCPD c th c nhng loi thc phm no? V nguyn tc 3-MCPD c th tm thy tt c nhng loi thc phm m qu trnh ch bin chng c s kt hp gia cht bo, axit chlohydric v gia nhit. X du (Tng): tng l mt loi thc phm quen dng c sn xut t qu trnh ln men v chuyn ho u tng bi vi sinh vt (Aspergillus oryzae or A. sojae), tuy nhin trong cng ngh sn xut hin nay ngi ta thng s dng nguyn liu l kh u tng ( tch du) ri thu phn bng axit chlohydric (HCl). u tng l mt loi u giu proteins v cht bo, v vy vic thu phn protein u tng bng axit HCl v nhng bc tip theo trong qu trnh ch bin tng thc y qu trnh to ra cht 3-MCPD. c tnh giu protein v cht bo lm cho tng sn xut theo phng php ny tr thnh mt ngun 3-MCPD cao nht so vi nhng thc phm khc. Thc phm khc c th cha 3-MCPD: Ng cc rang (lc, u) Malt en v dch chit malt en Sc-xch ln men 3-MCPD cng c th hnh thnh trong qu trnh nu nng thng thng kh clo trong nc (nhiu h thng nc dng kh clo x l) tip xc vi cht bo v c gia nhit trong qu trnh nu nng. nh hng ca cht 3-MCPD n sc kho con ngi v ng vt

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Phn ln nhng nghin cu v c tnh ca cht 3-MCPD c thc hin trn ng vt, vi sinh vt v cc dng t bo chun, trong c nhng nghin cu trn chut cho thy rng 3MCPD c kh nng gy ung th. Nhng nghin cu trn vi sinh vt v dng t bo cho thy 3MCPD c th lm thay i qu trnh nhn bn gene. 3- Gii hn cho php Trc y cc chuyn gia v thc phm ca lin minh chu u gi rng 3-MCPD phi mc khng th pht hin c bng phng php phn tch hin i nht (ni nm na l 3-MCPD khng c tn ti trong thc phm). Tuy nhin sau khi nhng nghin cu mi nht c cng b, cc chuyn gia ny khuyn co mc s dng ti a hng ngy (Tolerable Daily Intake) l 2ug/kg th trng. 4Phng php xc nh 3-MCPD trong thc phm

3-MCPD u tin s c tch khi thc phm, sau cho tc dng vi mt cht trung gian to thnh mt dn xut, dn xut ny sau c tch trn h thng sc k kh v phn tch bng phng php ph khi (GC/MS & GC/MS/MS). Do phn ng chuyn i trung gian c hiu sut thp v khng c nh vi cc ln lp li khc nhau, xc nh chnh xc hm lng 3-MCPD ngi ta phi s dng c ni chun (internal standard) v ngoi chun (external standard) Vi thc phm dng lng nh tng th ngi ta c th hp ph 3-MCPD (mu v ni chun nh du) ln cht hot ng b mt (diatomacous earth, zeolite) sau trch li bng diethyl ether, sau c c ri phn tch trn h thng GC/MS. 5Vn cng ng quan tm trnh s dng nc tng c cht lng khng m bo ngi tiu dng nn la chn tng ca nhng cng ty c uy tn v khng nm trong danh sch en cng b. Khng nn dng tng ca cng ty khng c ting tm bi l vic sn phm ca nhng cng ty ny khng nm trong danh sch en n gin ch v ngi ta cha ly mu phn tch m thi. Ngi tiu dng cng khng nn hoang mang khi mt s bi bo quy kt cho vic gia tng bnh nhn ung th l do 3-MCPD gy ra. V mt nguyn tc khi i sng pht trin, iu kin chm sc y t tt th t l ngi cht v ung th s tng ln. Nguyn nhn su xa nm ch, khi iu kin chm sc sc kho tt ln, t l ngi cht v nhng bnh thng thng s gim i, nh tui th cng cao hn. Khi tui th cao t l mc bnh ung th cng tng.