Bacterium Diseases Virulence Factors Diagnostic Tests Treatment Gm Motile?

Metabolism Special
Notes
Bacillus + Most Aerobic or Spore
rod are facultative formers
motile anaerobic
B. anthracis Cutaneous anthrax *plasmid encoded *cultures: long Penicillin no Facultative -the only
-95% of cases -polyglutamic serpentine chain anaerobic strict
-may disseminate to acid capsule *clinical specimen: -for PCN pathogen
septicemia -anthrax exotoxin single/paired bacilli; allergic:
Inhalation anthrax 1) edema factor NO spores! erythromycin,
-flu-like symp., high fever, 2) lethal factor *absence of hemolysis tetracycline,
dyspnea, hypotension 3) protective Ag & motility chloramphenicol
-hemorrhagic necrosis, -Gm stain or
bacteremia fluorescence Ag stain
-dead <24 hr. -biochem tests
Gastrointestinal anthrax
-fever, nausea, vomiting,
diarrhea
-shock & death

B. cereus -food poisoning ENTEROTOXINS -supportive Yes aerobic

-gastroenteritis -heat-labile  measures for
-ingestion of spores diarrhea food poisoning
-heat labile enterotoxin -heat-stable 
-long incubation emesis -for ocular
-intoxication infections:
-ingestion of heat- -Cereolysin vancomycin,
stable enterotoxin (hemosylin) gentamycin,
-short incubation -phospholipase C ciprofloxacin
-ocular infections (lecithinase)
-intravenous catheter- *resistant to
related sepsis *no capsule PCN &
cephalosporins