Scribd Logo
Upload

Welcome to Scribd!

  • Management Alogarithm of Pregnancy

    Uploaded by

    Utami Handayani
    11 views1 page
    The document provides guidelines for managing pregnancy in patients with thrombophilia. It recommends assessing risks before conception, stopping teratogenic drugs in advance, and coordinating care between hematologists and obstetricians. During pregnancy, low molecular weight heparin and aspirin are prescribed depending on risk level, with dosage adjustments throughout stages of pregnancy and postpartum. High-risk patients may additionally receive interferon alpha.

    Original Description:

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    The document provides guidelines for managing pregnancy in patients with thrombophilia. It recommends assessing risks before conception, stopping teratogenic drugs in advance, and coordinating care between hematologists and obstetricians. During pregnancy, low molecular weight heparin and aspirin are prescribed depending on risk level, with dosage adjustments throughout stages of pregnancy and postpartum. High-risk patients may additionally receive interferon alpha.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    11 views1 page

    Management Alogarithm of Pregnancy

    Uploaded by

    Utami Handayani
    The document provides guidelines for managing pregnancy in patients with thrombophilia. It recommends assessing risks before conception, stopping teratogenic drugs in advance, and coordinating care between hematologists and obstetricians. During pregnancy, low molecular weight heparin and aspirin are prescribed depending on risk level, with dosage adjustments throughout stages of pregnancy and postpartum. High-risk patients may additionally receive interferon alpha.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    of 1

    Planning pregnancy/preconception phase Asses risk (thrombophilia screen, family & personal history Stop possible teratogenic drugs

    gs (3 month wash out period) Joint care (hematologist/obstetrician)

    Pregnancy PV(Normal risk) Target Hct should be kept in the middle of normal range for gestation Platelet count <1000G/I Aspirin 50-100 mg/day LMWH after delivery until 6 weeks post partum

    Previous arterial event/ to replace warfarin/ actual thrombosis

    High risk pregnancy/ abnormal artery uterine doppler

    Aspirin 50-100mg/day LMWH twice daily throughout pregnancy + Interferon alpha

    Aspirin 50-100mg/day LMWH throughtout pregnancy At 16-20/40 increase to twice daily Consider interferon alpha

    Delivery Consider stopping aspirin 1-2 weeks prior to delivery Stop LMWH 12 hours (prophylactic LMWH) to 24 hours (therapeutic LMWH) before labor is accepted

    Postpartum Restart LMWH for 6 weeks Target HCT shall be keep in the middle of normal range

    Note: LMWH: Low Molecular Weight warfarin Enoxaparin 40mg/dalterparin 5000 IU High risk pregnancy: 1. Previous maternal major thromboembolic/major hemorarhagic complication 2. Severe cimplication 3. Platelet count >1000x109

    You might also like