Simplex Schizofrenia

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Nasratul ilmi 09020055

SIMPLEX SCHIZOFRENIA

Definition
An uncommon disorder in which there is an insidious but progressive development of oddities of conduct, inability to meet the

demands of society, and decline in total performance. It usually appear in puberty time.

Etiology
Endocrine Metabolism Adolf Meyer teory Sigmund freud teory Eugen Bleuler

Genetic
Neurochemistry Neurodevelopmental hypothesis

Symptoms
Delusions and hallucinations are not evident
The disorder is less obviously psychotic than

the hebephrenic, paranoid, and catatonic subtypes of schizophrenia The characteristic negative features of residual schizophrenia (e.g. blunting of affect, loss of volition) develop without being preceded by any overt psychotic symptoms.

Diagnosis
Simplex schizophrenia is a difficult diagnosis to make with any confidence because it depends on establishing the slowly

progressive development of the characteristic negative symptom. Without any history of hallucinations, delusions, or other manifestations of an earlier psychotic episode, and with significant changes in personal behaviour

Diagnosis
Currently there is no physical or lab test that can

absolutely diagnose schizophrenia.


A psychiatrist usually comes to the diagnosis

based on clinical symptoms.

Treatments
Psychotherapy - an adjunct to meds and is very useful to keep the patient on the meds.

Group therapy
Family therapy Community support groups

Treatment of Schizophrenia

The acute psychotic schizophrenic patients will respond usually to antipsychotic medication. According to current consensus we use in the first line therapy the newer atypical antipsychotics, because their use is not complicated by appearance of extrapyramidal side-effects, or these are much lower than with classical antipsychotics.
chlorpromazine, chlorprotixene, clopenthixole, levopromazine, periciazine, thioridazine
droperidole, flupentixol, fluphenazine, fluspirilene, haloperidol, melperone, oxyprothepine, penfluridol, perphenazine, pimozide, prochlorperazine, trifluoperazine amisulpiride, clozapine, olanzapine, quetiapine, risperidone, sertindole, sulpiride

conventional antipsychotics (classical neuroleptics) atypical antipsychotics

Prognosis
If we can treated well it can decrease life quality, can cause decline in occupation make them lose their, begger, criminal.

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