Scribd Logo
Upload

Welcome to Scribd!

  • Pathophysiology of Sporadic (Non-Toxic) Goiter: Pre-Disposing Facotrs Precipitating Factors

    Uploaded by

    czesmine
    21 views2 pages
    This document discusses the pre-disposing factors, precipitating factors, etiology, and pathophysiology of sporadic (non-toxic) goiter. Some key pre-disposing factors include being female, over 40 years old, having a family history of goiter, or living in mountainous or heavily rainy areas. Precipitating factors include a history of radiation therapy, intake of goitrogens, or excessive or deficient iodine levels. Iodine deficiency or excessive iodine intake can cause the thyroid gland to enlarge due to inability to secrete sufficient hormones. Over time the thyroid gland slowly increases in size which can lead to neck masses, pressure on surrounding structures, and symptoms like difficulty swallow

    Original Description:

    Original Title

    125192716 Path o Physiology

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    This document discusses the pre-disposing factors, precipitating factors, etiology, and pathophysiology of sporadic (non-toxic) goiter. Some key pre-disposing factors include being female, over 40 years old, having a family history of goiter, or living in mountainous or heavily rainy areas. Precipitating factors include a history of radiation therapy, intake of goitrogens, or excessive or deficient iodine levels. Iodine deficiency or excessive iodine intake can cause the thyroid gland to enlarge due to inability to secrete sufficient hormones. Over time the thyroid gland slowly increases in size which can lead to neck masses, pressure on surrounding structures, and symptoms like difficulty swallow

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    21 views2 pages

    Pathophysiology of Sporadic (Non-Toxic) Goiter: Pre-Disposing Facotrs Precipitating Factors

    Uploaded by

    czesmine
    This document discusses the pre-disposing factors, precipitating factors, etiology, and pathophysiology of sporadic (non-toxic) goiter. Some key pre-disposing factors include being female, over 40 years old, having a family history of goiter, or living in mountainous or heavily rainy areas. Precipitating factors include a history of radiation therapy, intake of goitrogens, or excessive or deficient iodine levels. Iodine deficiency or excessive iodine intake can cause the thyroid gland to enlarge due to inability to secrete sufficient hormones. Over time the thyroid gland slowly increases in size which can lead to neck masses, pressure on surrounding structures, and symptoms like difficulty swallow

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    of 2

    PRE-DISPOSING FACOTRS S SEX FEMALE (4:3 I 1:2 MALE) AGE OVER 40 YEARS OLD FAMILY HISTORY OF GOITER GEOGRAPHIC

    RAPHIC MOUTAIN AREAS OR HEAVY RAINFALL AREA

    PATHOPHYSIOLOGY OF SPORADIC (NON-TOXIC) GOITER

    PRECIPITATING FACTORS HISTORY OF RADIATION THERAPY REGULAR INTAKE OF GOITROGENS EXCESSIVE AMOUNT OFIODINE IODINE DEFICIENCY

    ETIOLOGY:MAYBE CAUSED BY ONE OF THE FACTORS STATED

    [IODINE DEFICIENCY] THYROID GLAND CANTT SECRETE ENOUGH THYROID HORMONE TO MEET METABOLLIC and GROWTH NEEDS [EXCESSIVE IODINE] TOO MUCH GOITROGENIC INGESTION DECREASES T4 (TETRAIODOTHYRONINE) PRODUCTION

    LACK IN IODINE DECREASES GLANDULAR ORGANIC IODINE LEVEL

    IMPAIRS IODINE HORMONE SYNTHESIS AND HYPOTHALAMUS TENDS TO INCREASE THE RELEASE TSH (THYROID STIMULATING HORMONE)

    WHEN THYROID HORMONE SECRETION IS REDUCED BELOW NORMAL LEVELS, SECRETION OF TSH RELEASING HORMONE AND TSH SECRETION SUBSTANTIALLY INCREASE.

    EXCESS TSH DEVELOP AREAS OF INVOLUSION AND DEVELOPS HYPERPLASIA

    DEVELOPMENT OF NODULES TAKES PLACE

    THYROID GLAND SLOWLY INCREASE IN SIZE

    DEVELOPMENT OF FUNCTIONAL THYROTOXICOSIS

    VISIBLE ANTERIOR NECK MASS

    PRESSURE ON ANTERIOR NECK STRUCTURES

    VENOUS OUTFLOW, OBSTRUCTION OF THE HEAD AND NECK CIRCULATION

    PRESSURE ON ESOPHAGUS

    PRESSURE ON TRACHEA

    PRESSURE ON RECURRENT LARYNGEAL NURVE

    FACIAL PLETHORA

    DYSPHAGIA

    DYSPNEA HOARSENESS COUGHING

    WHEEZING

    You might also like