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Lecture 4: Energy & Enzymes

Energy flow throught the biosphere

The Sun

High entropy energy

Low entropy energy

!G<0

Photosynthetic Organisms

High entropy energy

Low entropy energy

!G<0

Other Organisms

High entropy energy

Fig. 4-9

Free energy is the energy available to do work

!G = !H -T!S

Contributions of enthalpy and entropy

1. Fermentation of glucose to ethanol C6H12O6 (s) 2 C5H5OH (l) + CO2 (g)

2. Melting of ice H2O (l) H2O (g)

Enzymes

Exergonic reaction energy profile

Enzyme structure & catalysis

E + S

ES

E + P

But how do enzymes lower EA?

Enzymes & Growth rate

How is the tertinary sturcture of enzymes different among these four types of organisms?

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