Path o Physiology

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Pathophysiology

Non modifiable Age Family history

Modifiable Obesity Decreased activity High fat diet High sugar diet (softdrinks)

Type 2 Diabetes

Insufficient insulin production

Insulin resistance

Hyperglycemia

Increased blood viscosity

Blood sugar exceeds renal threshold Glycosuria Glucose cannot enter cells

Decreased blood flow

Favours bacterial growth

Hypertension

Decreased tissue perfusion in lower extremities

Infection

Osmotic diuresis

Cellular starvation

Pneumonia UTI Slow healing of wounds and discoloration of feet

Increased urine output

Sensation of hunger

Polyuria Polyphagia

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