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  • Pathophysiology Final

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    Modifiable risk factors for gallstone formation include diet, lifestyle, and ingestion of high cholesterol foods. The liver helps digest cholesterol, but excess cholesterol can lead to gallstone formation when cholesterol precipitates out of bile to form crystals. Gallstones may block the cystic duct leading to pain, and migration of a gallstone can cause inflammation of the gallbladder or acute cholecystitis presenting with severe right upper quadrant pain.

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    PATHOPHYSIOLOGY FINAL

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    PATHOPHYSIOLOGY FINAL

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    Modifiable risk factors for gallstone formation include diet, lifestyle, and ingestion of high cholesterol foods. The liver helps digest cholesterol, but excess cholesterol can lead to gallstone formation when cholesterol precipitates out of bile to form crystals. Gallstones may block the cystic duct leading to pain, and migration of a gallstone can cause inflammation of the gallbladder or acute cholecystitis presenting with severe right upper quadrant pain.

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    85 views2 pages

    Pathophysiology Final

    Uploaded by

    larissedeleon
    Modifiable risk factors for gallstone formation include diet, lifestyle, and ingestion of high cholesterol foods. The liver helps digest cholesterol, but excess cholesterol can lead to gallstone formation when cholesterol precipitates out of bile to form crystals. Gallstones may block the cystic duct leading to pain, and migration of a gallstone can cause inflammation of the gallbladder or acute cholecystitis presenting with severe right upper quadrant pain.

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    of 2

    VI.

    Pathophysiology
    Modifiable Factor: Diet Lifestyle Ingestion of high cholesterol foods Non-Modifiable Factor: Age Genes

    Liver with help of bilirubin will digest cholesterol

    Excess Cholesterol

    Cholesterol in normal levels is constituent of bile and Insoluble in water

    Increase bile acid synthesis Depends on bile acids and lecithin (phospholipids) Precipitates out of the bile to form crystal stones

    Formation of gallstones

    Increase irritant that produces inflammatory changes in gallbladder

    Migration of a gallstone into the opening of the cystic duct may block the outflow of bile during gallbladder contraction.

    Severe pain in the right upper quadrant, the pain is referred to as biliary colic

    Increase number and size of gallstones

    Increase in gallbladder wall tension produces a characteristic type of pain.

    Cystic duct obstruction

    Acute gallbladder inflammation (Acute cholecystitis)

    (Acute cholecystitis Pain in the right upper quadrant

    Pain Scale of 9/10

    Jaundice

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