NAME OF DRUG ( GENERIC AND BRAND NAME) Generic Name: Cefuroxime Brand Name: Cefrin, Zinacef Classification: Antibiotic,

Cephalosporin

DOSAGE, ROUTE, FREQUENC Y 500 mg PO BID

INDICATION/ ACTION

CONTRAADVERSE EFFECT INDICATION

NURSING RESPONSIBILITY W/ RATIONALE

INDICATION: Treatment of infections of lower respiratory tract, urinary tract, skin and skin structures; treatment of uncomplicated gonorrhea, otitis media, pharyngitis, and tonsillitis caused by susceptible strains of specific microorganisms.

ACTION: Bactericidal action against susceptible bacteria. Pleural and synovial fluid, sputum, bone and aqueous fluids; CSF (therapeutic concentrations). Crosses the placenta and enters breast milk. Protein-binding: Up to 50%

CONTRAGI INDICATION: Nausea; vomiting; diarrhea; anorexia; abdominal pain or Contraindicate cramps; flatulence; colitis, d in patients including pseudomembranous hypersensitive colitis. to drug or Genitourinary other Pyuria; renal dysfunction; cephalosporin. dysuria; reversible interstitial nephritis; hematuria; toxic Use cautiously nephropathy. in patients Hematologic hypersensitive Eosinophilia; neutropenia; to penicillin lymphocytosis; leukocytosis; because of thrombocytopenia; decreased possibility of platelet function; anemia; crossaplastic anemia; hemorrhage. sensitivity with Hepatic other beta Hepatic dysfunction; lactam abnormal LFT results. antibiotics Miscellaneous Hypersensitivity, including Stevens-Johnson syndrome, erythema multiforme,

Before: Assess for previous history of reactions to other cephalosporin or penicillin. ( Theres possibility of cross-sensitivity with other beta-lactam antibiotics) Before giving the first dose, obtain specimen for culture and sensitivity test. (To ensure right drug) During: Swallow tablets whole; do not crush them. Take the drug with food(Taking the drug with food can mask the taste of the medication) Advise patient to maintain normal fluid intake while using this medication. (Fluid ease swallowing and facilitate absorption from gastrointestinal tract)

After: Be alert for adverse reaction and drug interaction(to establish proper precautionary measures and management for possible adverse effects of the drug) If GI reactions occur, monitor pts hydration(To prevent dehydration)