Nuclear domains provide localized regions of funtion for the actiities that occu r in the nucleus 1.

DNE replication Can incorporate fluorescent dNTPs DNA replication pattern: -Incorporate one fluorescent dye during early S-phase (DNA Synthesis) and a diff erent dye during late S-phase *More of the first dye is then found *Regions of high density of DNA are replicated first (With the first dye) *Low gene density if replicated later (second dye) -DNA replication is ORGANIZED 2.Transcription