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    This document discusses neglected diseases, which are diseases that primarily affect impoverished populations in developing countries. Neglected diseases thrive in tropical environments where poor living conditions and limited access to healthcare exist. The "big three" neglected diseases that receive the majority of funding are HIV/AIDS, tuberculosis, and malaria. However, many other neglected tropical diseases (NTDs) exist that receive far less attention and funding from pharmaceutical companies due to them not representing profitable drug markets. Common features of NTDs include that they disproportionately impact those in poverty. The document also addresses why pharmacies are reluctant to research NTDs and provides an overview of some example NTDs like podoconiosis.

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    This document discusses neglected diseases, which are diseases that primarily affect impoverished populations in developing countries. Neglected diseases thrive in tropical environments where poor living conditions and limited access to healthcare exist. The "big three" neglected diseases that receive the majority of funding are HIV/AIDS, tuberculosis, and malaria. However, many other neglected tropical diseases (NTDs) exist that receive far less attention and funding from pharmaceutical companies due to them not representing profitable drug markets. Common features of NTDs include that they disproportionately impact those in poverty. The document also addresses why pharmacies are reluctant to research NTDs and provides an overview of some example NTDs like podoconiosis.

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    9 views16 pages

    Lecture 1 Neglected Disease

    Uploaded by

    Abu Ridhuwan
    This document discusses neglected diseases, which are diseases that primarily affect impoverished populations in developing countries. Neglected diseases thrive in tropical environments where poor living conditions and limited access to healthcare exist. The "big three" neglected diseases that receive the majority of funding are HIV/AIDS, tuberculosis, and malaria. However, many other neglected tropical diseases (NTDs) exist that receive far less attention and funding from pharmaceutical companies due to them not representing profitable drug markets. Common features of NTDs include that they disproportionately impact those in poverty. The document also addresses why pharmacies are reluctant to research NTDs and provides an overview of some example NTDs like podoconiosis.

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    of 16

    NEGLECTED DISEASE

    Teguh Marfen Djajakusumah, dr., MKes., SpB (K)V

    DEFINITION
    Global health organizations define neglected diseases as those that are prevalent among impoverished and marginalized populations in the developing world. Tropical environments, poor living conditions, and limited access to health care contribute to the risk and spread of these diseases.

    http://www.ott.nih.gov/Technologies/NegDis_ovrvw.aspx

    WHY NEGLECTED?

    WHY TROPICAL AND DEVELOPING COUNTRIES?

    http://www.sciencephoto.com/media/183846/enlarge

    THE BIG THREE


    HIV/AIDS TBC

    Malaria
    Nearly 80% of 2.5 billion dollar went to the big three!

    Frew SE, Liu VY, Singer PA. A business Plan to help the global south in its fight against neglected disease. Health Aff (Millwood). 2009;28(6):176073

    COMMON FEATURES OF NTD

    * First WHO report on NTD, 2010

    COMMON FEATURES OF NTD

    WHY PHARMACIES ARE RELUCTANT TO NTDS?


    NTDs are not an attractive market for pharmaceutical industries

    The patent system


    Limited fund for research

    J Med Ethics 2009;35:310314. doi:10.1136/jme.2008.027078

    LIST OF NTDS

    Podoconiosis

    NTDS TODAY

    http://www.neglecteddiseases.gov/

    GROUP ASSIGNMENT
    Group I : Neglected Disease

    An overview of neglected disease


    Why the diseases termed as neglected? With what diseases should it be compared with? What implication that some diseases have been neglected in medical research? Group II: The high cost of drug discovery An overview about drug discovery (including vaccine development)

    Why drug discovery become very expensive?


    What do you think of it? What should medical community should do about it?

    GROUP ASSIGNMENT
    Group III: Life style drug and Me-too drug

    An overview of life -style drugs


    Why the world spend more money on life-style drugs Why do life-style drugs receive more attention from pharmaceutical company than other drugs? Give examples on how the money has been spent on life -style drugs compared to others Me-too drugs

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