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النيورو دكتور محمد الشافعي يااااااااااااااااا رب
النيورو دكتور محمد الشافعي يااااااااااااااااا رب
النيورو دكتور محمد الشافعي يااااااااااااااااا رب
:
: : : :
......
.....
.....
neurology
neurology
... neurology
neurology
Neurology
neurology
neurology
....................................................................
Neurology
Nervous tissue
central nervous system
peripheral nervous system
....................................................................
section brain gray matter
white matter
gray matter
nerve cells
white matter
axons nerve cells
white matter
collection of gray matter basal ganglion
gray matter white matter
surface brain
sulci gyri
surface area
sulci gyri
sulci gyri
( )
( )
sulci gyri
brain print
finger print
sound print
larynx
iris
contact lenses
brain print MRI
.... 100 ....
....................................................................
MRI
account
MRI
sulci gyri
sulci
sulci
lateral sulcus
central sulcus
parieto-occipital sulucs
sulci
sulci brain
frontal lobe
parietal lobe
temporal lobe
occipital lobe
!!!!
neurologist 18 brain function
neurologists meeting
neurology autopsy
hemiplegia
autopsy
movement
Hemiplegia
neurology ....
neurologists
neuro (
)
hemiplegia
( ) .... autopsy
( )
( ) damaged
( ) frontal lobe
( )
communication
brain areas
....................................................................
brain areas
brain functions
brain areas
... areas functions areas
function
function
!!!!!
brain
....
....
function brain areas
emotions
( )
emotions Memory Intelligence
functions areas
( brain )
function areas
area function
....................................................................
face
Lower limb
damage Area 4 function
hemiplegia
damage Area 4
hemiplegia Area 4 mono plegia
tumor .... damage of lower limb area extend damage
upper limb extend damage Face
Infarction .... Area 4 Infarction
Infarction paralysis upper limb Lower limb
....................................................................
hemiplegia Damage
Motor Jacksonian fits Irritation
descending ascending
Area 4
Area 6 Area Area 4
Area 6
Opposite side of the body tone Inhibition Area 4
Area 6
damage
Opposite side of the body hyper tonia Inhibtion
Area 6
upper motor neuron lesion Babinski
dorsi flexion of the big toe
...... Fanning
is dorsi flexion of big toe with or without fanning ..... Babinski
dorsi flexion of big toe +ve Babinski
Area 6 fanning
opposite side of the body hyper tonia Damage Area 6
fanning of the lateral 4 toes on eliciting the planter reflex
) (
....................................................................
Lesion
Opposite side irritation
Damage the same side of the lesion
(
)
irritation
damage
( ..... ( ) Involuntary .....
.... )
Area 8 Area 4
Area 4 and Area 8 damage
Area 4 damage hemiplegia
same side of the lesion away from the hemiplegic limb
....
damage
Area 4 and Area 8 Irritation
Area 8 irritation Opposite side of the lesion
Area 4 irritation Motor Jacksonian fits
patient to the side of Jacksonian fits
the patient is amazed
Area
Area )occupying the whole frontal lobe (......
Area 44
Female
female
speech
frontal lobe females
....................................................................
Broca's area
Area 44
expressive aphasia
.... ..... Larynx
paralyzed
conscious level
Area 44
I cannot express my ideas by spoken words
(
- :-! .. : .. :
.. !) ..
Area 44 Area 45
Area 45 Males
........
....................................................................
lack of concentration
dis-interest in people and surroundings ..
loss of personal hygiene ....
loss of personal hygiene
urinate
defecate
defecate
consent
Loss of consent of social hygiene
amnesia lack of concentration disinterest in people and surroundings
loss of personal hygiene
pre frontal area
pre frontal area
superior frontal gyrus
reflexes primitive reflexes sucking
sucking
grasping
reflexes
Inhibit the primitive reflexes
damage pre frontal area
reappearance of the primitive reflexes
sucking reflex
.... grasping reflex
):
reflex
damage Pre frontal area mentality, personality, behaviour changes and loss of
personal hygiene reappearance of primitive reflexes
Parietal lobe
mirror image frontal
....................................................................
Area 4 Motor
parietal lobe Area 1, 2 and 3 sensory
Area 4 body represented upside down
Area 1,2 and 3 body represented upside down
Damage Area 4 Hemiplegia
Damage of Area 1, 2 and 3 hemianathesia
Irritation Area 4 Motor Jacksonian fits
Irritation Area 1,2 and 3 Sensory Jacksonian fits
Sensory Jacksonian fits tingling and numbness
face
face
Area 1, 2 and 3 Mirror image Area 4
....................................................................
Damage Area 39
Area 37
Area 37 Area
parietal lobe
Area 37
coordination
coordination Two cerebral hemisphere Area 37
coordinate two cerebral hemisphere
Area 37 loss of coordination
Area 37 ...... ....
Order
( )
failure of coordination
Apraxia
failure of coordination Level Motor
Level ideas
which is usual ....
(
" "
" " "
"
:
:
....................................................................
: " : "
" : "
" : "
) 67
!!!!!
cerebral hemi sphere
cerebral hemi sphere
two cerebral hemi sphere idea
coordination two cerebral hemi sphere Idea
Area 37
Area 37
word salad
.... (
)
language
.... word salad
enough
word salad
situation
Language
Area 37 Apraxia and word salad
word salad Jargon's aphasia
Temporal lobe
Temporal lobe
....................................................................
Areas of the brain
Neurology Areas of the brain
brain tumors
frontal lobe tumors
frontal lobe
Damage irritation tumor
Irritation
Motor Jacksonian fits Area 4
irritation Area 6
conjugate eye movement to the opposite side Area 8
irritation Area 44
Irritation Area 45
irritation pre frontal
Damage
Hemiplegia Area 4
fanning Area 6
paralysis of the conjugate eye movement to the opposite side Area 8
expressive aphasia Area 44
agraphia Area 45
mentality, personality and behaviour changes
frontal lobe Infarction
Damage infarction
Paralysis of the conjugate eye movement fanning hemiplegia
expressive aphasia agraphia mentality, personality and behaviour change
frontal lobe epilepsy
Irritation
conjugate eye movement to the opposite side Motor Jacksonian fits
Areas
) (
brain
Damage Irritation :
Damage :
clinical pictures :
....................................................................
Areas
Temporal lobe
uncus hippocampus
uncus smell
Uncus Uncus
uncus
uncus
Uncus
( ) Uncus Uncus
Damage Uncus loss of the smell ...
smell is bilaterally represented
so damage to the uncus does not produce loss of the smell
uncus Irritation
olfactory hallucinations
olfactory hallucinations
Damage to the uncus Loss of the smell bilaterally
irritation olfactory hallucinations
....................................................................
Area
Area 22
Area
....
Area 41 and Area 42
Area 22 ...
...
....
Area 22
Area 22
Auditory agnosia
Auditory agnosia
( )
.... Auditory agnosia
Uncus
agnosia
... auditory agnosia
Area 22
Occipital lobe
Area 17, Area 18 and Area 19
Area 17
Area 18
Area 19
....................................................................
Area 17
Area 18
17 18
Area 19
... ...
18 ):
17 18 19
Area 41 and 42
Area 22
Area 37
Area 37 Area 18 :
Area 37 Area 44
speech
fraction of seconds
Brain
brain
....................................................................
):
Brain ( )
response of the brain
( : :
- : - : )
Areas
neurology
neurology
Anatomy of the motor system
):
Anatomy of the motor system
Motor area 4
frontal lobe
Area 4 body represented Upside down
Cells of area 4
( ) Axon ( )
Area 4 Pyramid
fibers Area 4 pyramidal fibers
( cells Area 4 ) Pyramid
fibers area 4 pyramidal fibers
brain
internal capsule
Internal capsule fibers brain
anterior limb posterior limb genu
genu
Pyramidal tract genu
adjoining part of anterior and posterior limbs
anterior posterior limbs
....................................................................
fibers brain stem
( )
fibers
crossing medulla
80 % fibers crossing Opposite side
20 %
Pyramidal tract
opposite side
2cerebral hemisphere brain stem
opposite
Pyramidal tract
cranial nuclei
7th and 12th opposite side
....................................................................
Area 4
pyramidal tract
supply
Anterior horn cells
Nerves
Muscles
Upper motor neuron system
Area 4 Pyramidal tract
lower motor neuron system
anterior horn cells nerves muscles
....................................................................
:
16
atrophic
16
disuse atrophy
Tone
tone
Tone
biceps 6 cm
Origin Insertion biceps 8 cm
biceps Origin Insertion stretch
Origin insertion
is stretched
stretched
( muscle fibers ) Muscle fibers Impulses
dorsal root ganglion
dorsal root ganglion spinal cord
Axon
T shaped
fibers impulses dorsal root ganglion
dorsal root ganglion Posterior horn cells
posterior horn cells Anterior horn cells
....................................................................
Anterior horn cells nerve fibers
contract
Is contracting
disuse atrophy
tone
Pyramidal
pyramidal tone Inhibition
( ) ): biceps (
) biceps tone
biceps tone
Pyramidal tone
tone
atrophy
pyramidal tract tone Inhibition
pyramidal tract Inhibition lost
Lost
tone
hyper tonia
Pyramidal tract
Level of the lesion Hyper tonia
nerve stretch
impulses contract
nerve Upper Lower
Lower
Lower motor neuron lesion
tone Lost Nerve
tone
Nerve lesion Lower motor neuron lesion
tone hypo tonia Lost
....................................................................
lower motor neuron lesion
hypo tonia at the level of the lesion
hyper tonia upper motor neuron lesion
tone muscle wasting
wasted muscle
muscle wasting Upper motor neuron lesion
Hypo tonia lower motor neuron lesion
muscle wasting
Tone
Muscle wasting
No muscle wasting Upper motor neuron lesion
Lower motor neuron lesion
there is muscle wasting
deep reflexes ankle knee triceps biceps deep reflexes
deep reflex
biceps
tendon
contract
stretch tendon
dorsal root ganglion
post horn cells dorsal root ganglion
Anterior horn cells
....................................................................
contract
deep reflex Tone
Tone muscle fibers
deep reflex muscle
Tone is spontaneous
deep reflex is induced
):
((:
tone deep reflex
Upper motor neuron lesion hyper reflexia
Lower motor neuron lesion hypo reflexia
Clonus
Upper motor neuron lesion
Upper motor neuron lesion clonus
tendon stretched upper motor neuron lesion
hyper reflexia stretch tendon muscle contract
contraction
clonus exaggerated reflex
Upper motor neuron lesion Lower motor neuron lesion
clonus sustained stretch contraction
Pathological reflexes
Upper motor neuron lesion
Pathological reflexes
Pathological reflex adductor reflex
....................................................................
tubercle adductor tendon
adductor tubercle Normal
contraction contraction
contraction
clinical contract
contract .... tendons stretch
normal
clinically contract
upper and lower motor neuron lesion
....................................................................
Upper motor neuron lesion
tone hyper tonia
wasting Muscle wasting
clonus
pathological reflexes
Babinski +ve
lower motor neuron lesion
Babinski planter flexion
there is no negative Babinski
negative Babinski
planter flexion
Upper motor neuron lesion
Babinski Positive
Lower motor neuron lesion
planter flexion
):
superficial reflexes is lost Upper motor and lower motor
Upper motor neuron lesion Hyper tonia , hyper reflexia
superficial reflexes Upper motor neuron lesion loss of superficial
reflexes
Upper motor neuron lesion lower motor neuron lesion loss of superficial
reflexes
upper and lower motor neuron lesion
( ) 11
anatomy
...
):
Pathway motor neuron system
motor system
....................................................................
pyramidal tract
...
pyramidal
Extra pyramidal emotions
(:
):
tone
emotions Extra pyramidal
Muscle
pyramidal
Area 4
(
)
( Cerebellum )
Cerebellum brain
pyramidal
Pyramidal cerebellum
kinetic tremor
motor system
Extra pyramidal emotions
....................................................................
cerebellum
Sensations
Sensory pathways
sensations
Somatic
visceral
special sense ( vision, hearing, taste and smell)
Cranial nerves
Cranial nerves special senses
....................................................................
Pain
visceral pain is poorly localized
Poorly localized
myocardial infraction anterior wall
Pain
pain
visceral pain
Somatic pain
!!!!!
15 appendix
15 appendix
15
): Pain
Pain appendix visceral pain
inflammation wall appendix
Peritoneum somatic pain
Inflammation wall
appendix
Chest pain
ECG
...
pericarditis Pleurisy Muscle
cardic
cardic visceral pain
angina Pain closed fist
Somatic sensation
somatic sensation sensation skin pleura pericardium
Peritoneum
....................................................................
body covering
Somatic sensation
somatic sensation
superficial
deep
cortical
females
females
:
):
)):
....................................................................
females
females
)):
Somatic sensation
superficial
deep
cortical
superficial sensation
pain & temperature
pain & temperature
sensation receptors
receptors Nerve endings
nerve
receptor pain and temperature Nerve endings dorsal root
ganglion
Tone
Axon T shaped
Peripheral part
central part
Lateral part
Medial part
....................................................................
dorsal root ganglion
Medial branch
spinal cord
spinal cord few segments ( Lissauer's tract )
sensation
Lesion
lesion
sensation
sensation
lesion Level
Lesion
which means sensation the level of the lesion
sensation Level of the lesion
pain temperature few segments
Lissauer's tract
....................................................................
fibers thalamus
spino-thalamic fibers
spino thalamic
lateral spino-thalamic
fibers brain stem thalamus
lateral lemniscus
fibers
brain stem
Muhammad
Lateral lemniscus lesion
brain stem
lateral spino-thalamic tract lesion
spinal cord
thalamus fibers area
Area 1, 2 and 3
(
)
pain and temperature
deep sensation
deep sensation
muscle sense, joint sense, nerve sense and vibration sense
deep sensation
Pathway
):
....................................................................
deep sensation pathway
dorsal root ganglion
thalamus
superficial
Dorsal root ganglion
thalamus
Substantia Gelatinosa of Rolandi
Gracile and Cuneate deep sensation
spinal cord crossing superficial
Medulla crossing deep sensation
lateral lemniscus pain & temperature
Medial lemniscus deep sensation
!!!!!!
....................................................................
Pathway superficial deep sensation
touch
:
crude touch
fine touch
crude touch superficial
fine touch deep
crude touch superficial sensation
fine touch deep sensation
cortical
superficial deep sensation
Area 1,2 and 3
( ) ):
):
( )
( ) :
joint sense
brain
brain smooth
ridges touch
... cold temperature
Area Area 1, 2 and 3
superficial and deep sensation
cortical sensation
....................................................................
cortical sensation
combination superficial and deep sensation
Stereognosis
Stereognosis
hemiplegia Loss of superficial sensation
cortical
:
: cortical superficial deep intact
cortical sensation superficial deep sensation
30
microscopic structure submicroscopic structures
30 35
cortical sensation lost superficial deep sensation
He has his opinion which might be proven by time later on.
cortical superficial deep sensation
round
....................................................................
cortical superficial deep
cortical superficial deep
pathway superficial pathway deep sensation
Upper motor neuron lesion & lower motor neuron lesion
cranial nerves
Olfactory nerve
Mucosa posterior 1/3
Mucosa anterior 2/3 smell
smell
Mucosa posterior 1/3
nerve fibers
Penetrate cribriform plate
Olfactory bulb
olfactory tract
Area uncus
Lobe temporal lobe
uncus
uncus
Lesion olfactory nerve
Anosmia
Loss of smell
Anosmia Lesion Mucosa
nerve
Lesion Mucosa atrophic rhinitis
Lesion fracture base skull
Lesion Nerve tumor meningioma
Anosmia unilateral
Anosmia bilateral
....................................................................
atrophic rhinitis unilateral bilateral bilateral
fracture base of the skull Unilateral bilateral Unilateral bilateral
trauma Lateral unilateral
trauma central bilateral
Meningioma unilateral bilateral ( ) bilateral
!!!! bilateral meningioma
Meningioma unilateral
tumor
Unilateral
causes of bilateral anosmia
Atrophic rhinitis
fracture base of the skull
hysterical
hysterical
hysterical coma
comatosed
Epilepsy
to gain sympathy
hysterical to gain sympathy
coma
!!!!!
):
hysterical anosmia
hysterical anosmia
hysterical coma
comatosed
hysterical anosmia
hysterical coma
....................................................................
causes of unilateral anosmia
tumor Inferior surface of the frontal lobe
anosmia optic atrophy
tumor Intra cranial pressure
papilloedema
Foster-Kennedy Syndrome
MCQ
Foster-Kennedy Syndrome
Lesion
Parosmia
Perfume
: perfume ...
....................................................................
bad smell
Post traumatic
head trauma
post traumatic
.
Parosmia
Olfactory Hallucinations
irritation
uncus
bad smell
irritation uncus
temporal lobe epilepsy
Epilepsy irritation
Lesions Olfactory nerve
MCQ
cranial nerve
Optic nerve
Optic nerve vision
eye
eye Retina
Retina Rods Cons vision
Eye
Nasal nose
Temporal
temporal Nasal
Nasal Temporal
....................................................................
Nasal Nasal
Nasal Nasal
Nose
Temporal nasal over riding nose
Nasal temporal
Nasal half fibers
temporal half fibers
Optic nerve
Optic nerve
Blindness ipsilateral
Both fibers
fibers Optic Chiasma
Optic chiasma Nasal fibers
crossing opposite side
Nasal fibers
crossing opposite side
Optic chiasma
Nasal fibers of both eyes
Optic chiasma
Nasal fibers
field temporal
Bi temporal hemianopia
temporal
Temporal field
temporal field
Bi temporal hemianopia
Temporal field
fibers Optic chiasma
fibers Optic chiasma
neurology
....................................................................
fibers
fibers
pituitary fossa
tumor Pituitary fossa
intrasellar tumors upper quadrantic bi temporal hemianopia
suprasellar tumor produce lower quadrantic bi temporal hemianopia
Optic chiasma
Bi temporal hemianopia
fibers Optic tract
Optic tract
temporal fibers
Nasal fibers
Optic tract
field
filed nasal
temporal fibers nasal field
fibers
Nasal
field temporal
Optic tract
field
Nasal field
Field temporal
( nasal fibers crossing ) optic chiasma
....................................................................
Optic tract
....................................................................
Occipital lobe
macula
Macula
macula Occipital lobe
Occipital lobe
Posterior cerebral artery artery supplied
supplied Occipital lobe
Posterior cerebral artery
Macula Area
supplied by posterior cerebral artery
middle cerebral artery artery
macula area
double blood supply
Posterior cerebral artery
Occipital lobe Infarction
Macula
sparing Macula
....
Contra lateral homonymous hemianopia with macula sparing
Occipital lobe tumor
Contra lateral homonymous hemianopia with macula affection
Occipital lobe Lesion
lesion
vascular
Contra lateral homonymous hemianopia with macula sparing
macula has double blood supply
tumor
Contra lateral homonymous hemianopia with macula affection
....................................................................
!!!!!!!!!!!
light reflex
( torch )
constriction
constriction
direct torch
constriction indirect consensual
pathway light reflex
Light
Impulses retina
Optic nerve
Optic chiasma
Optic tract
fibers light reflex Optic tract
lateral geniculate body
stimulation
activation retina
Impulses Optic nerve
Optic chiasma
Optic tract
lateral geniculate body
fibers Optic tract
Mid brain
Mid brain nucleus Pretectal nucleus
pretectal nucleus
( Mid brain tectum ) tegmentum
pretectal nucleus
Impulses cranial nerve
constriction
constriction
fibers aqueduct of Sylvius
Aqueduct of Sylvius
two lateral ventricles CSF
....................................................................
third ventricle
Aqueduct of Sylvius
4th ventricle
Aqueduct of Sylvius
fibers
Peri aqueductal fibers
aqueduct of Sylivus
Cranial nerve
Nucleus Edinger- Westphal nucleus
Pathway
Light reflex
stimulation
Optic nerve
Lost direct Indirect
Light Light
....................................................................
( )
Optic chiasma
Bitemporal hemianopia
temporal field
Light temporal Light reflex
nasal Light reflex
Light reflex
Light
stimulation temporal Nasal
Optic chiasma
field light reflex
hemianopic pupillary reaction
hemianopic pupillary reaction
light reflex
Light
stimulation
Optic tract
hemianopic pupillary reaction
activation
light light reflex
Light reflex hemianopic pupillary reaction
fibers lateral geniculate body
(
...
)
Occipital lobe
Light reflex Occipital lobe
....................................................................
Accommodation ( near ) reflex
convergence
constriction of the pupil
and contraction of ciliary muscle
Accommodation reflex
Pathway
( ) Pathway
Impulse Retina
Optic nerve
Optic chiasma
Optic tract
lateral geniculate body
Occipital lobe
visual pathway
Occipital lobe
cranial nerve
light pathway
Accommodation reflex is
visual + light
Optic nerve
MCQ
cranial nerve
3rd, 4th and 6th
brain stem Motor nuclei
Mid brain Nuclei 3rd and 4th
Pons Nuclei 5th, 6th and 7th
Medulla Nuclei 9th, 10th, 11th and 12th
....................................................................
Mid brain
cranial nerve 6
abducnet nerve
nucleus
Nucleus Pons
Abducent nerve
nucleus Pons
Nerve fibers
supply
lateral rectus muscle
anatomy
Anatomy
Abducent nerve
( ): )
Nerve supply
..... nerve
nerve supply
Nerve
supply
nerve
petrous bone
petrous bone middle cranial fossa
middle and inner ear
nerve
Nerve
Abducent
intra cranial pressure
crushing
Nerve Increased intra cranial pressure
abducent nerve
supply
Lateral rectus muscle
....................................................................
lateral rectus
laterally
abduction
abducent nerve
abduction
lateral rectus
brain
Lateral rectus
...
Diplopia
abducent
patient diplopia
when he looks in the direction of the paralyzed muscle
paralyzed muscle
Lateral rectus
direction
diplopia
when he looks in the direction of paralyzed muscle
abducent MCQ
abducent
Increased intra cranial tension
....................................................................
()A smile is a language that even a baby understands.
Cranial nerve
The Trochlear nerve
trochlear nerve
cranial nerve
Nucleus Mid brain
trochlear Nucleus Mid brain
fibers supply supperior oblique
superior oblique
superior oblique downward and inward
neurology
textbook
neurology
Updating
Neurology
updating
updating
....................................................................
ICU
ICU
ICU
Neurology
status eplipticus
One of the most intelligent definition that has been written in myoclonic epilepsy has been
written by an egyptian doctor called Elwan
neurology
Neurology
brain
!!!!!!!!
!!!!!!!!!!! !!!!!
....................................................................
70
( )
semester
320
320
( )
17
( )
17
....................................................................
!!!!!
Just for fun
fun
Haematology
!!!!!!!!!!!!
:
RBCs
( )
12
....................................................................
)
Trochlear nerve
Nucleus mid brain
fibers supply supperior oblique
downward and inward
down ward and inward
trochlear
superior oblique
tendon
superior orbital margin
notch
Notch cartilage
tendon notch
superior olbique
notch superior orbital margin
cartilage
tendon Notch
notch cartilage
trochlea
trochlear nerve
tendon trochlea
MCQ
....................................................................
Cranial nerve
Oculomotor nerve
eye
superior rectus
Inferior rectus
medial rectus
Lateral rectus
superior oblique
Inferior oblique
lateral rectus
Abducent nerve
superior oblique
trochlear nerve
Oculomotor nerve
supply
superior rectus, inferior rectus, medial rectus, inferior oblique and elevator palpebrae
superioris
elevator palpebrae superioris
Upper lid
cranial nerve
constrictor pupillae muscle of the iris
ciliary muscle of the lens
constrictor pupillae muscle of the iris
constriction of pupil
ciliary muscle of the lens
lens contraction
change the shape of the lens
....................................................................
cranial nerve
Oculomotor nerve
supply
Oculomotor
cranial nerve
lateral rectus superior oblique
Oculomotor nerve
outward Lateral rectus
downward superior oblique
Oculomotor
Out ward and downward
diplopia
diplopia
!!!!!
diplopia
Ptosis
diplopia
elevator palpebrae superioris
ptosis
diplopia!!!!!!!!!
diplopia eye lid
diplopia
Upward and inward
Oculomotor
....................................................................
fixed
does not respond to light reflex
light reflex constriction
constrictor
dilated fixed
fixed
does not respond to light reflex
loss of accommodation
ciliary muscle of the lens
Oculomotor nerve
( )
fibers Oculomotor nerve supply the extra occular muscle
fibers Oculomotor nerve supply the intra occular muscle
fibers supply
fibers supply
neurology
tumor cranial nerve
Intra occular muscle
dilated fixed pupil
tumor
....................................................................
Ischemia Occulomotor nerve
diabetes
microangiopathy
Oculomotor nerve
extra occular muscles Intra occular muscle
lesion