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  • DM Dewasa Kuliah

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    VinaSanthira
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    This document discusses type 2 diabetes mellitus (DM). It covers several topics in 3 paragraphs or less: 1) It outlines some of the problems associated with increased prevalence of DM like chronic complications such as diabetic foot. Prevention strategies are mentioned. 2) Causes of insulin resistance and beta-cell dysfunction are summarized, including factors like obesity, physical inactivity, genetics, lipotoxicity, and glucose toxicity. 3) Risk factors for type 2 diabetes are listed, including genetic factors, gestational diabetes, increasing age, central obesity, physical inactivity, and diet. The pathophysiology and major cardiovascular complications of type 2 diabetes are also briefly discussed.

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    Dm Dewasa Kuliah

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    Dm Dewasa Kuliah

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    This document discusses type 2 diabetes mellitus (DM). It covers several topics in 3 paragraphs or less: 1) It outlines some of the problems associated with increased prevalence of DM like chronic complications such as diabetic foot. Prevention strategies are mentioned. 2) Causes of insulin resistance and beta-cell dysfunction are summarized, including factors like obesity, physical inactivity, genetics, lipotoxicity, and glucose toxicity. 3) Risk factors for type 2 diabetes are listed, including genetic factors, gestational diabetes, increasing age, central obesity, physical inactivity, and diet. The pathophysiology and major cardiovascular complications of type 2 diabetes are also briefly discussed.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    10 views8 pages

    DM Dewasa Kuliah

    Uploaded by

    VinaSanthira
    This document discusses type 2 diabetes mellitus (DM). It covers several topics in 3 paragraphs or less: 1) It outlines some of the problems associated with increased prevalence of DM like chronic complications such as diabetic foot. Prevention strategies are mentioned. 2) Causes of insulin resistance and beta-cell dysfunction are summarized, including factors like obesity, physical inactivity, genetics, lipotoxicity, and glucose toxicity. 3) Risk factors for type 2 diabetes are listed, including genetic factors, gestational diabetes, increasing age, central obesity, physical inactivity, and diet. The pathophysiology and major cardiovascular complications of type 2 diabetes are also briefly discussed.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    of 8

    DM Dewasa

    EVA DECROLI
    Problems
    Increased of prevalence
    Cronic complications
    ex. Diabetic Foot
    Problems
    Prevention, primer, secunder
    tertier
    Etiology of Insulin Resistence
    Weight gain
    Obexisity
    Circulation FFA
    Lipoatrophy
    adipokines
    Insulin Resistance
    The subnormal biologic response to
    a given concentration of insulin
    Physical
    inactivity
    Aging
    Genetica
    Etiology of -Cell Dysfunction
    Genetics
    Lipotoxicity
    Glucose
    toxicity
    -Cell Failure
    Inadequate compentation for insulin
    resistance and selective
    non-responsivoness to glucose
    Loss of
    -cell ?
    Cytokines ?
    Amyloid
    accumulation
    The Role of Genes and the Environment
    Normal
    GENES
    Environment
    Insulin
    resistance
    Diabetes genes
    insulin resistance genes
    -cel function genes
    Obesity genes
    Decreased Insulin
    secretion
    Type DM

    Diet Activity
    Toxins
    Risk Factors for Type 2 Diabetes
    Genetic factors
    -Ethnicity
    -Family history
    Gastational
    Diabetes polycystic
    Ovarian syndrome,
    and party
    Type 2
    Diabetes
    Increasing
    age
    Central
    obesity
    Physical
    inactivity
    Diet
    Pathophysiology of DM
    Hepatic glucose
    Production (HGP
    Peripheral Glucose
    Uptake
    Blood Glucose
    Macrovascular Complication of
    Type 2 Diabetes
    80% of people with type 2 diabetes thr from CVD
    ~ Coronary heart disease (CHD)
    - eg, angina, heart attack, heart failure
    - 2-to 4-fold increased risk
    ~ Cerebrovascular disease
    - eg, stroke, transient ischemic attacks
    - 2-to 4-foid increased risk
    ~ Peripheral vascular disease
    - eg. Intermittent claudication, gangrene,
    amputations

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