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    A process is described for preparing highly pure (S)-pregabalin containing less than 5 ppm of cyanide ions or free from cyanide ions. This is achieved by extracting the cyano diester intermediate of (S)-pregabalin using a solvent, which removes cyanide ions. The purified intermediate is then hydrolyzed to obtain (S)-pregabalin in high purity without cyanide ion contamination.

    Original Description:

    WO 2010061403

    Original Title

    WO 2010 061403

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    A process is described for preparing highly pure (S)-pregabalin containing less than 5 ppm of cyanide ions or free from cyanide ions. This is achieved by extracting the cyano diester intermediate of (S)-pregabalin using a solvent, which removes cyanide ions. The purified intermediate is then hydrolyzed to obtain (S)-pregabalin in high purity without cyanide ion contamination.

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    © All Rights Reserved
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    14 views22 pages

    This Patent PDF Generated by Patent Fetcher (R), A Service of Stroke of Color, Inc

    Uploaded by

    sunil_vaman_joshi
    A process is described for preparing highly pure (S)-pregabalin containing less than 5 ppm of cyanide ions or free from cyanide ions. This is achieved by extracting the cyano diester intermediate of (S)-pregabalin using a solvent, which removes cyanide ions. The purified intermediate is then hydrolyzed to obtain (S)-pregabalin in high purity without cyanide ion contamination.

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    © All Rights Reserved
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    of 22

    WO2010061403

    Publication Title:
    PROCESS TO PREPARE HIGHLY PURE (S)-PREGABALIN
    Abstract:
    Abstract of WO 2010061403
    (A2) Translate this text A process for the preparation of (S)-pregabalin of formula
    I containing cyanide ion content less than 5 ppm or free from the cyanide ion,by
    extracting its cyano diester intermediate of formula III, wherein R
    ------------
    Courtesy of http://v3.espacenet.com
    This Patent PDF Generated by Patent Fetcher(R), a service of Stroke of Color, Inc.

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