Cervical Cancer

CLD-BOMP Bleomycin, I.V., 5 mg continuous infusion, days 1-7

Cisplatin, I.V., 10 mg/m
2
, day 1, 22
Vincristine, I.V., 0.7 mg/m
2
, day 7
Mitomycin-C. I.V., 7 mg/m
2
, day 7
RC - every 21 days

MOBP Bleomycin, I.V., 30 units/day continuous infusion, days 1, 4
Vincristine, I.V., 0.5 mg/m
2
, days 1, 4
Mitomycin-C. I.V., 10 mg/m
2
, day 1
Cisplatin, I.V., 50 mg/m
2
, days 1, 22
RC - every 28 days

Endometrial Cancer

AP Doxorubicin, I.V., 60 mg/m
2
, day 1
Cisplatin, I.V., 60 mg/m
2
, day 1
RC - every 21 days

Adenocarcinoma
Carbo-Tax Paclitaxel, I.V., 135 mg/m
2
over 24 hours, day 1, followed by
Carboplatin dose targeted by Calvert equation to AUC 7.5 I.V.
RC - every 21 days

EP Cisplatin, I.V., 60-100 mg/m
2
, day 1
Etoposide, I.V., 80-100 mg/m
2
, days 1-3
RC - every 21 days

FAM Fluorouracil, I.V., 600 mg/m
2
, days 1, 8, 29, 36
Doxorubicin, I.V., 30 mg/m
2
, days 1, 29
Mitomycin, I.V., 10 mg/m
2
, day 1
RC - every 8 weeks

PCE Paclitaxel, I.V., 200 mg/m
2
over 1 hour, day 1, followed by
Carboplatin dose targeted by Calvert equation to AUC 6 I.V.
Etoposide, P.O., 50 mg/day alternated with 100 mg/day, days 1-10
RC - every 21 days
Breast Cancer

AC Doxorubicin, I.V., 60 mg/m
2
, day 1
Cyclophosphamide, I.V., 400-600 mg/m
2
, day 1
RC - every 21 days

Ace Doxorubicin, I.V., 40 mg/m
2
, day 1
Cyclophosphamide, P.O., 200 mg/m
2
/day, days 1-3 or 3-6
RC - every 21-28 days

CAF Cyclophosphamide, P.O., 100 mg/m
2
, days 1-14 or 600 mg/m
2
I.V., day 1
Doxorubicin, I.V., 25 mg/m
2
, days 1, 8 or 60 mg/m
2
I.V., day 1
Fluorouracil, I.V., 500-600 mg/m
2
, days 1, 8
RC - every 28 days

CFM Cyclophosphamide, I.V., 500-600 mg/m
2
, day 1
Fluorouracil, I.V., 500-600 mg/m
2
, day 1
Mitoxantrone, I.V., 10-12 mg/m
2
, day 1
RC - every 21 days

CFPT Cyclophosphamide, I.V., 150 mg/m
2
, days 1-5
Fluorouracil, I.V., 300 mg/m
2
, days 1-5
Prednisone, P.O., 10 mg tid, days 1-7
Tamoxifen, P.O., 10 mg bid, days 1-42
RC - every 42 days

CMF Cyclophosphamide, P.O., 100 mg/m
2
, days 1-14 or 600 mg/m
2
I.V., days 1, 8
Methotrexate, I.V., 40 mg/m
2
, days 1, 8
Fluorouracil, I.V., 600 mg/m
2
, days 1, 8
RC - every 28 days

CMFP Cyclophosphamide, P.O., 100 mg/m
2
, days 1-14
Methotrexate, I.V., 40-60 mg/m
2
, days 1, 8
Fluorouracil, I.V., 600-700 mg/m
2
, days 1, 8
Prednisone, P.O., 40 mg (first 3 cycles only), days 1-14
RC - every 28 days

FAC Fluorouracil, I.V., 500 mg/m
2
, days 1, 8
Doxorubicin, I.V., 50 mg/m
2
, day 1
Cyclophosphamide, I.V., 500 mg/m
2
, day 1
RC - every 21 days

IMF Ifosfamide, I.V., 1.5 g/m
2
, days 1, 8
Mesna, I.V., 20% of ifosfamide dose, days 1, 8
Methotrexate, I.V., 40 mg/m
2
, days 1, 8
Fluorouracil, I.V., 600 mg/m
2
, days 1, 8
RC - every 28 days
NFL Mitoxantrone, I.V., 12 mg/m
2
, day 1
Fluorouracil, I.V., 350 mg/m
2
, days 1-3, given after leucovorin calcium
Leucovorin calcium, I.V., 300 mg/m
2
, days 1-3

VATH Vinblastine, I.V., 4.5 mg/m
2
, day 1
Doxorubicin, I.V., 45 mg/m
2
, day 1
Thiotepa, I.V., 12 mg/m
2
, day 1
Fluoxymesterone, P.O., 10 mg tid, days 1-21
RC - every 21 days

Colon Cancer

F-CL Fluorouracil, I.V., 375 mg/m
2
, days 1-5
Leucovorin calcium, I.V., 200 mg/m
2
, days 1-5
RC - every 28 days

Fle Fluorouracil, I.V., 450 mg/m
2
for 5 days
Levamisole, P.O., 50 mg tid for 3 days

FMV Fluorouracil, I.V., 10 mg/kg/day, days 1-5
Methyl-CCNU, P.O., 175 mg/m
2
, day 1
Vincristine, I.V., 1 mg/m
2
(max: 2 mg), day 1
RC - every 35 days

FU/LV Fluorouracil, I.V., 370-400 mg/m
2
/day, days 1-5
Leucovorin calcium, I.V., 200 mg/m
2
/day.
RC - every 21 days

5FU/LDLF Fluorouracil, I.V., 425 mg/m
2
/day, days 1-5
Leucovorin calcium, I.V., 20-25 mg/m
2
/day, days 1-5
RC - every 28 days

Gastric Cancer

EAP Etoposide, I.V., 120 mg/m
2
, days 4, 5, 6
Doxorubicin, I.V., 20 mg/m
2
, days 1, 7
Cisplatin, I.V., 40 mg/m
2
, days 2, 8
RC - every 28 days

ELF Leucovorin calcium, I.V., 300 mg/m
2
, days 1-3 followed by
Etoposide, I.V., 120 mg/m
2
, days 1-3 followed by
Fluorouracil, I.V., 500 mg/m
2
, days 1-3
RC - every 21-28 days

FAM Fluorouracil, I.V., 600 mg/m
2
, days 1, 8, 29, 36
Doxorubicin, I.V., 30 mg/m
2
, days 1, 29
Mitomycin C, I.V., 10 mg/m
2
, day 1
RC - every 8 weeks

FAME Fluorouracil, I.V., 350 mg/m
2
, days 1-5, 36-40
Doxorubicin, I.V., 40 mg/m
2
, days 1, 36
Methyl-CCNU, P.O., 150 mg/m
2
, day 1
RC - every 70 days

FAMTX Methotrexate, IVPB, 1500 mg/m
2
, day 1
Fluorouracil, IVPB, 1500 mg/m
2
1 hour after methotrexate, day 1
Leucovorin calcium, P.O., 15 mg/m
2
q6h x 48 hours, 24 hours after methotrexate, day 2
Doxorubicin, IVPB, 30 mg/m
2
, day 15
RC - every 28 days

FCE Fluorouracil, I.V., 900 mg/m
2
/day continuous infusion, days 1-5
Cisplatin, I.V., 20 mg/m
2
, days 1-5
Etoposide, I.V., 90 mg/m
2
, days 1, 3, 5
RC - every 21 days
PFL Cisplatin, I.V., 25 mg/m
2
continuous infusion, days 1-5
Fluorouracil, I.V., 800 mg/m
2
continuous infusion, days 2-5
Leucovorin calcium, I.V., 500 mg/m
2
continuous infusion, days 1-5
RC - every 28 days

Head and Neck Cancer

CAP Cyclophosphamide, I.V., 500 mg/m
2
, day 1
Doxorubicin, I.V., 50 mg/m
2
, day 1
Cisplatin, I.V., 50 mg/m
2
, day 1
RC - every 28 days

CF Cisplatin, I.V., 100 mg/m
2
, day 1
Fluorouracil, I.V., 1000 mg/m
2
/day continuous infusion, days 1-5
RC - every 21-28 days

CF Carboplatin, I.V., 400 mg/m
2
, day 1
Fluorouracil, I.V., 1000 mg/m
2
/day continuous infusion, days 1-5
RC - every 21-28 days

COB Cisplatin, I.V., 100 mg/m
2
, day 1
Vincristine, I.V., 1 mg/m
2
, days 2, 5
Bleomycin, I.V., 30 units/day continuous infusion, days 2-5
RC - every 21 days

5-FU HURT Hydroxyurea, P.O., 1000 mg q12h x 11 doses
Fluorouracil, I.V., 800 mg/m
2
/day
Paclitaxel, I.V., 5-25 mg/m
2
/day
G-CSF, S.C., 5 mcg/kg/day,

PFL Cisplatin, I.V., 100 mg/m
2
, day 1
Fluorouracil, I.V., 600-800 mg/m
2
/day continuous infusion, days 1-5
Leucovorin calcium, I.V., 200-300 mg/m
2
/day, days 1-5
RC - every 21 days

PFL+IFN Cisplatin, I.V., 100 mg/m
2
, day 1
Fluorouracil, I.V., 640 mg/m
2
/day continuous infusion, days 1-5
Leucovorin calcium, P.O., 100 mg q4h, days 1-5
Interferon alfa-2b, S.C., 2 x 10
6
units/m
2
, days 1-6

TIP Paclitaxel, I.V., 175 mg/m
2
3-hour infusion, day1
Ifosfamide, I.V., 1000 mg/m
2
2-hour infusion, days 1-3
Mesna, I.V., 400 mg/m
2
before ifosfamide and 200 mg/m
2
I.V., 4 hours after ifosfamide
Cisplatin, I.V., 60 mg/m
2
, day 1
RC - every 21-28 days

Bladder Cancer

CAP Cyclophosphamide, I.V., 400 mg/m
2
, day 1
Doxorubicin, I.V., 40 mg/m
2
, day 1
Cisplatin, I.V., 60 mg/m
2
, day 1
RC - every 21 days

CISCA Cisplatin, I.V., 70-100 mg/m
2
, day 2
Cyclophosphamide, I.V., 650 mg/m
2
, day 1
Doxorubicin, I.V., 50 mg/m
2
, day 1
RC - every 21-28 days
CMV Cisplatin, I.V., 100 mg/m
2
over 4 hours, start 12 hours after MTX, day 2
Methotrexate, I.V., 30 mg/m
2
, days 1, 8
Vinblastine, I.V., 4 mg/m
2
, days 1, 8
RC - every 21 days

m-PFL Methotrexate, I.V., 60 mg/m
2
, day 1
Cisplatin, I.V., 25 mg/m
2
continuous infusion, days 2-6
Fluorouracil, I.V., 800 mg/m
2
continuous infusion, days 2-6
Leucovorin calcium, I.V., 500 mg/m
2
continuous infusion, days 2-6
RC - every 28 days for 4 cycles

MVAC Methotrexate, I.V., 30 mg/m
2
, days 1, 15, 22
Vinblastine, I.V., 3 mg/m
2
, days 2, 15, 22
Doxorubicin, I.V., 30 mg/m
2
, day 2
Cisplatin, I.V., 70 mg/m
2
, day 2
RC - every 28 days

PC Paclitaxel, I.V., 200 mg/m
2
or 225 mg/m
2
over 3 hours, day 1
Carboplatin, I.V.
RC - every 21 days

Ovarian Cancer

Carbo-Tax Paclitaxel, I.V., 135 mg/m
2
over 24 hours, day 1
Carboplatin dose targeted by Calvert equation to AUC 7.5 I.V.
RC - every 21 days

CC Carboplatin, I.V., dose targeted by Calvert equation to AUC 6-7
Cyclophosphamide, I.V., 600 mg/m
2
, day 1
RC - every 28 days

CP Cyclophosphamide, I.V., 750 mg/m
2
, day 1
Cisplatin, I.V., 75 mg/m
2
, day 1
RC - every 21 days

CT Paclitaxel, I.V., 135 mg/m
2
over 24 hours, day 1
Cisplatin, I.V., 75 mg/m
2

RC - every 21 days

PAC (CAP) Cisplatin, I.V., 50 mg/m
2
, day 1
Doxorubicin, I.V., 50 mg/m
2
, day 1
Cyclophosphamide, I.V., 750 mg/m
2
, day 1
RC - every 21 days x 8 cycles

BEP Bleomycin, I.V., 30 units, days 2, 9, 16
Etoposide, I.V., 100 mg/m
2
, days 1-5
Cisplatin, I.V., 20 mg/m
2
, days 1-5

VAC Vincristine, I.V., 1.2-1.5 mg/m
2
every 2 weeks for 12 doses
Dactinomycin, I.V., 0.3-0.4 mg/m
2
, days 1-5
Cyclophosphamide, I.V., 150 mg/m
2
, days 1-5
Repeat every 28 days
Prostate
EV Estramustine, P.O., 200 mg tid, days 1-42
Vinblastine, I.V., 4 mg/m
2
/week, begin day 1
RC - every 6 weeks
FL Flutamide, P.O., 250 mg tid, days 1-28
Leuprolide acetate, S.C., 1 mg qd, days 1-28
RC - every 28 days

FZ Flutamide, P.O., 250 mg tid
Goserelin acetate, S.C., 3.6 mg implant, every 28 days or goserelin S.C.,
10.8 mg depot every 12 weeks

L-VAM Leuprolide acetate, S.C., 1 mg qd, days 1-28
Vinblastine, I.V., 1.5 mg/m
2
/day continuous infusion, days 2-7
Doxorubicin, I.V., 50 mg/m
2
continuous infusion, day 1
Mitomycin C, I.V., 10 mg/m
2
, day 2
RC - every 28 days

Testicular Cancer
EP Etoposide, I.V., 100 mg/m
2
, days 1-5
Cisplatin, I.V., 20 mg/m
2
, days 1-5
RC - every 21 days

BEP Bleomycin, I.V., 30 units, days 2, 9, 16
Etoposide, I.V., 100 mg/m
2
, days 1-5
Cisplatin, I.V., 20 mg/m
2
, days 1-5
RC - every 21 days

PVB Cisplatin, I.V., 20 mg/m
2
, days 1-5
Vinblastine, I.V., 0.15 mg/kg, days 1, 2
Bleomycin, I.V., 30 units, days 2, 9, 16
RC - every 21 days

VIP Etoposide, I.V., 75 mg/m
2
, days 1-5
Ifosfamide, I.V., 1.2 g/m
2
, days 1-5
Cisplatin, I.V., 20 mg/m
2
, days 1-5
Mesna, I.V., 400 mg/m
2
, then 1200 mg/m
2
/day continuous infusion, days 1-5
RC - every 21 days

VIP Vinblastine, I.V., 0.11 mg/kg, days 1-2
Ifosfamide, I.V., 1200 mg/m
2
, days 1-5
Cisplatin, I.V., 20 mg/m
2
, days 1-5
Mesna, I.V., 400 mg/m
2
, then 1200 mg/m
2
/day continuous infusion, days 1-5
RC - every 21 days

VAB VI Vinblastine, I.V., 4 mg/m
2
, day 1
Dactinomycin, I.V., 1 mg/m
2
, day 1
Bleomycin, I.V., 30 units
Cisplatin, I.V., 120 mg/m
2
, day 4
Cyclophosphamide, I.V., 600 mg/m
2
, day 1
RC - every 21 days

VBP (PVB) Vinblastine, I.V., 6 mg/m
2
, days 1, 2
Bleomycin, I.V., 30 units, days 1, 8, 15, (22)
Cisplatin, I.V., 20 mg/m
2
, days 1-5
RC - every 21-28 days

DMC Dactinomycin, I.V., 0.37 mg/m
2
, days 1-5
Methotrexate, I.V., 11 mg/m
2
, days 1-5
Cyclophosphamide, I.V., 110 mg/m
2
, days 1-5
RC - every 21 days
Leukemias

VAD Vincristine, I.V., 0.4 mg continuous infusion, days 1-4
Doxorubicin, I.V., 12 mg/m
2
continuous infusion, days 1-4
Dexamethasone, P.O., 40 mg, days 1-4, 9-12, 17-20

VP Vincristine, I.V., 2 mg/m
2
/week for 4-6 weeks (max: 2 mg)
Prednisone, P.O., 60 mg/m
2
/day in divided doses for 4 weeks, taper weeks 5-7

VP-L-Asparaginase Vincristine, I.V., 2 mg/m
2
/week for 4-6 weeks (max: 2 mg)
Prednisone, P.O., 60 mg/m
2
/day for 4-6 weeks, then taper
L-asparaginase, I.V., 10,000 units/m
2
/day

MM Mercaptopurine, P.O., 50-75 mg/m
2
, days 1-7
Methotrexate, P.O./I.V., 20 mg/m
2
, day 1
RC - every 7 days

MMC Methotrexate, I.V., 20 mg/m
2
/week
Mercaptopurine, P.O., 50 mg/m
2
/day
Cyclophosphamide, I.V., 200 mg/m
2
/week

AVDP Asparaginase, I.V., 15,000 units/m
2

Vincristine, I.V., 2 mg/m
2

Daunorubicin, I.V., 30-60 mg/m
2

Prednisone, P.O., 40 mg/m
2


DAT/DCT Daunorubicin, I.V., 60 mg/m
2
/day, days 1-3
Cytarabine, I.V., 200 mg/m
2
/day continuous infusion, days 1-5
Thioguanine, P.O., 100 mg/m
2
q12h, days 1-5

EMA-86 Etoposide, I.V., 200 mg/m
2
/day continuous infusion, days 8-10
Mitoxantrone, I.V., 12 mg/m
2
, days 1-3
Cytarabine, I.V., 500 mg/m
2
/day continuous infusion, days 1-3, 8-10

IC Idarubicin, I.V., 12 mg/m
2
/day, days 1-3
Cytarabine, I.V., 100-200 mg/m
2
/day continuous infusion, days 1-7

MC Mitoxantrone, I.V., 12 mg/m
2
/day, days 1-3
Cytarabine, I.V., 100-200 mg/m
2
/day continuous infusion, days 1-7
Consolidation
Mitoxantrone, I.V., 12 mg/m
2
, days 1-2
Cytarabine, I.V., 100 mg/m
2
continuous infusion, days 1-5
RC - every 28 days

MV Mitoxantrone, I.V., 10 mg/m
2
/day, days 1-5
Etoposide, I.V., 100 mg/m
2
/day, days 1-3
CD Cytarabine, I.V., 3000 mg/m
2
q12h, days 1-6
Daunorubicin, I.V., 30 mg/m
2
/day, days 7-9


Chronic Lymphocytic Leukemia

CHL + PRED Chlorambucil, P.O., 0.4 mg/kg/day
Prednisone, P.O., 100 mg/day

CVP Cyclophosphamide, P.O., 400 mg/m
2
/day, days 1-5
Vincristine, I.V., 1.4 mg/m
2
(max: 2 mg), day 1
Prednisone, P.O., 100 mg/m
2
, days 1-5
RC - every 21 days

Small Cell Lung CA

CAV/VAC Cyclophosphamide, I.V., 750-1000 mg/m
2
, day 1
Doxorubicin, I.V., 50 mg/m
2
, day 1
Vincristine, I.V., 1.4 mg/m
2
(max: 2 mg), day 1
RC - every 3 weeks

CAVE Cyclophosphamide, I.V., 750 mg/m
2
, day 1
Doxorubicin, I.V., 50 mg/m
2
, day 1
Vincristine, I.V., 1.4 mg/m
2
(max: 2 mg), day 1
Etoposide, I.V., 60-100 mg/m
2
, days 1-3
RC - every 21 days

EC Etoposide, I.V., 100-120 mg/m
2
, days 1-3
Carboplatin, I.V., 325-400 mg/m
2
, day 1
RC - every 28 days

EP/PE Etoposide, I.V., 120 mg/m
2
, days 1-3
Cisplatin, I.V., 60-120 mg/m
2
, day 1
RC - every 21-28 days

Hodgkin's Lymphoma

ABVD Doxorubicin, I.V., 25 mg/m
2
, days 1, 15
Bleomycin, I.V., 10 units/m
2
, days 1, 15
Vinblastine, I.V., 6 mg/m
2
, days 1, 15
Dacarbazine, I.V., 150 mg/m
2
, days 1-5

ChlVPP Chlorambucil, P.O., 6 mg/m
2
(max: 10 mg/day), days 1-14
Vinblastine, I.V., 6 mg/m
2
(max: 10 mg dose), days 1, 8
Procarbazine, P.O., 100 mg/m
2
(max: 150 mg/day), days 1-14
Prednisone, P.O., 40 mg/day, days 1-14
RC - every 28 days

CVPP Lomustine, P.O., 75 mg/m
2
, day 1
Vinblastine, I.V., 4 mg/m
2
, days 1, 8
Procarbazine, P.O., 100 mg/m
2
, days 1-14
Prednisone, P.O., 30 mg/m
2
, days 1-14 (cycles 1 and 4 only)
RC - every 28 days

DHAP Dexamethasone, P.O./I.V., 40 mg, days 1-4
Cytarabine, I.V., 2 g/m
2
, q12h for 2 doses, day 2
Cisplatin, I.V., 100 mg/m
2
continuous infusion, day 1
RC - every 3-4 weeks

EVA Etoposide, I.V., 100 mg/m
2
, days 1-3
Vinblastine, I.V., 6 mg/m
2
, day 1
Doxorubicin, I.V., 50 mg/m
2
, day 1
RC - every 28 days

MOPP Mechlorethamine, I.V., 6 mg/m
2
, days 1, 8
Vincristine, I.V., 1.4 mg/m
2
(max: 2.5 mg), days 1, 8
Procarbazine, P.O., 100 mg/m
2
, days 1-14
Prednisone, P.O., 40 mg/m
2
(cycles 1 and 4 only), days 1-14
RC - every 28 days

MVPP Mechlorethamine, I.V., 6 mg/m
2
, days 1, 8
Vinblastine, I.V., 6 mg/m
2
, days 1, 8
Procarbazine, P.O., 100 mg/m
2
, days 1-14
Prednisone, P.O., 40 mg/m
2
, days 1-14
RC - every 42 days
NOVP Mitoxantrone, I.V., 10 mg/m
2
, day 1
Vincristine, I.V., 2 mg, day 8
Vinblastine, I.V., 6 mg/m
2
, day 1
Prednisone, P.O., 100 mg/m
2
, days 1-5
RC - every 21 days

Non-Hodgkin's Lymphoma

BACOP Bleomycin, I.V., 5 units/m
2
, days 15, 22
Doxorubicin, I.V., 25 mg/m
2
, days 1, 8
Cyclophosphamide, I.V., 650 mg/m
2
, days 1, 8
Vincristine, I.V., 1.4 mg/m
2
(max: 2 mg), days 1, 8
Prednisone, P.O., 60 mg/m
2
, days 15-28
RC - every 28 days

CHOP Cyclophosphamide, I.V., 750 mg/m
2
, day 1
Doxorubicin, I.V., 50 mg/m
2
, day 1
Vincristine, I.V., 1.4 mg/m
2
(max: 2 mg), day 1
Prednisone, P.O., 100 mg/m
2
, days 1-5
RC - every 21 days

CHOP-Bleo Cyclophosphamide, I.V., 750 mg/m
2
, day 1
Doxorubicin, I.V., 50 mg/m
2
, day 1
Vincristine, I.V., 2 mg, days 1, 5
Prednisone, P.O., 100 mg, days 1-5
Bleomycin, I.V., 15 units, days 1, 5
RC - every 21-28 days

CNOP Cyclophosphamide, I.V., 750 mg/m
2
, day 1
Mitoxantrone, I.V., 10 mg/m
2
, day 1
Vincristine, I.V., 1.4 mg/m
2
, day 1
Prednisone, P.O., 50 mg/m
2
, days 1-5
RC - every 21 days

COMLA Cyclophosphamide, I.V., 1500 mg/m
2

Vincristine, I.V., 1.4 mg/m
2
(max: 2.5 mg)
Methotrexate, I.V., 120 mg/m
2
,
Leucovorin calcium rescue, P.O., 25 mg/m
2
, q6h for 4 doses,
Cytarabine, I.V., 300 mg/m
2
, days 22, 29, 36, 43, 50, 57, 64, 71
RC - every 21 days

COP Cyclophosphamide, I.V., 800 mg/m
2
, day 1
Vincristine, I.V., 1.4 mg/m
2
(max: 2 mg), day 1
Prednisone, P.O., 60 mg/m
2
, days 1-5
RC - every 21 days

COP-BLAM Cyclophosphamide, I.V., 400 mg/m
2
, day 1
Vincristine, I.V., 1 mg/m
2
, day 1
Prednisone, P.O., 40 mg/m
2
, days 1-10
Bleomycin, I.V., 15 mg, day 14
Doxorubicin, I.V., 40 mg/m
2
, day 1
Procarbazine, P.O., 100 mg/m
2
, days 1-10

COPP Cyclophosphamide, I.V., 400-650 mg/m
2
, days 1, 8
Vincristine, I.V., 1.4-1.5 mg/m
2
(max: 2 mg), days 1, 8
Procarbazine, P.O., 100 mg/m
2
, days 1-14
Prednisone, P.O., 40 mg/m
2
, days 1-14
RC - every 28 days

CVP Cyclophosphamide, P.O., 400 mg/m
2
, days 1-5
Vincristine, I.V., 1.4 mg/m
2
(max: 2 mg), day 1
Prednisone, P.O., 100 mg/m
2
, days 1-5
RC - every 21 days

DHAP Dexamethasone, I.V., 10 mg q6h, days 1-4
Cytarabine, I.V., 2 g/m
2
q12h x 2 doses, day 2
Cisplatin, I.V., 100 mg/m
2
continuous infusion, day 1
RC - every 21-28 days

ESHAP Etoposide, I.V., 60 mg/m
2
, days 1-4
Cisplatin, I.V., 25 mg/m
2
continuous infusion, days 1-4
Cytarabine, I.V., 2 g/m
2

Methylprednisolone, I.V., 500 mg/day, days 1-4
RC - every 21-28 days

IMVP-16 Ifosfamide, I.V., 4 g/m
2

Mesna, I.V., 800 mg/m
2
bolus
Methotrexate, I.V., 30 mg/m
2
, days 3, 10
Etoposide, I.V., 100 mg/m
2
, days 1-3
RC - every 21-28 days

MACOP-B Methotrexate, I.V., 400 mg/m
2

Doxorubicin, I.V., 50 mg/m
2
Cyclophosphamide, I.V., 350 mg/m
2

Vincristine, I.V., 1.4 mg/m
2
(max: 2 mg)
Bleomycin, I.V., 10 units/m
2

Prednisone, P.O., 75 mg/day
Leucovorin calcium, P.O., 15 mg/m
2

Trimethoprim/sulfamethoxazole DS, P.O., tablet
Ketoconazole, P.O., 200 mg/day

m-BACOD Methotrexate, I.V., 200 mg/m
2
, days 8, 15
Leucovorin calcium, P.O., 10 mg/m
2
q6h x 8 doses
Bleomycin, I.V., 4 units/m
2
, day 1
Doxorubicin, I.V., 45 mg/m
2
, day 1
Cyclophosphamide, I.V., 600 mg/m
2
, day 1
Vincristine, I.V., 1 mg/m
2
, day 1
Dexamethasone, P.O., 6 mg/m
2
, days 1-5
RC - every 21 days

m-BACOS Methotrexate, I.V., 1 g/m
2
, day 2
Bleomycin, I.V., 10 units/m
2
, day 1
Doxorubicin, I.V., 50 mg/m
2
continuous infusion, day 1
Cyclophosphamide, I.V., 750 mg/m
2
, day 1
Vincristine, I.V., 1.4 mg/m
2
(max: 2 mg), day 1
Leucovorin calcium rescue, P.O., 15 mg q6h for 8 doses, starting 24 hours after methotrexate
Methylprednisolone, I.V., 500 mg, days 1-3

MINE Mesna, I.V., 1.33 g/m
2
/day
Ifosfamide, I.V., 1.33 g/m
2
/day, days 1-3
Mitoxantrone, I.V., 8 mg/m
2
, day 1
Etoposide, I.V., 65 mg/m
2
/day, days 1-3
RC - every 28 days

MINE-ESHAP Mesna, I.V., 1.33 g/m
2

Ifosfamide, I.V., 1.33 g/m
2
, over 1 hour, days 1-3
Mitoxantrone, I.V., 8 mg/m
2
, day 1
Etoposide, I.V., 65 mg/m
2
, days 1-3

NOVP Mitoxantrone, I.V., 10 mg/m
2
, day 1
Vinblastine, I.V., 6 mg/m
2
, day 1
Prednisone, P.O., 100 mg, days 1-5
Vincristine, I.V., 2 mg, day 8
RC - every 21 days

Pro-MACE Prednisone, P.O., 60 mg/m
2
, days 1-14
Methotrexate, I.V., 1.5 g/m
2
, day 14
Leucovorin calcium, I.V., 50 mg/m
2

Doxorubicin, I.V., 25 mg/m
2
, days 1, 8
Cyclophosphamide, I.V., 650 mg/m
2
, days 1, 8
Etoposide, I.V., 120 mg/m
2
, days 1, 8
RC - every 28 days

Malignant Melanoma
CVD Cisplatin, I.V., 20 mg/m
2
, days 1-5
Vinblastine, I.V., 1.6 mg/m
2
, days 1-5
Dacarbazine, I.V., 800 mg/m
2
, day 1
RC - every 21 days

CVD + IL-21 Cisplatin, I.V., 20 mg/m
2
/day, days 1-4
Vinblastine, I.V., 1.6 mg/m
2
/day, days 1-4
Dacarbazine, I.V., 800 mg/m
2
, day 1
IL-2, I.V., 9 million units/m
2
continuous infusion, days 1-4
Interferon alfa, S.C., 5 million units/m
2
, every day, days 1-5, 7, 9, 11, 13
RC - every 21 days

Multiple Myeloma

EDAP Etoposide, I.V., 100-200 mg/m
2
, days 1-4
Dexamethasone, P.O./I.V., 40 mg/m
2
, days 1-5
Cytarabine, 1000 mg, day 5
Cisplatin, I.V., 20 mg continuous infusion, days 1-4

MP Melphalan, P.O., 8-10 mg/m
2
, days 1-4
Prednisone, P.O., 40-60 mg/m
2
/day, days 1-4
RC - every 28-42 days

VAD Vincristine, I.V., 0.4 mg/day continuous infusion, days 1-4
Doxorubicin, I.V., 9 mg/m
2
/day continuous infusion, days 1-4
Dexamethasone, P.O., 40 mg, days 1-4, 9-12, 17-20
RC - every 28-35 days

VBAP Vincristine, I.V., 1 mg, day 1
Carmustine, I.V., 30 mg/m
2
, day 1
Doxorubicin, I.V., 30 mg/m
2
, day 1
Prednisone, P.O., 100 mg, days 1-4
RC - every 21 days

VBMCP Vincristine, I.V., 1.2 mg/m
2
, day 1
Carmustine, I.V., 20 mg/m
2
, day 1
Melphalan, P.O., 8 mg/m
2
, days 1-4
Cyclophosphamide, I.V., 400 mg/m
2
, day 1
Prednisone, P.O., 40 mg/m
2

RC - every 35 days

VCAP Vincristine, I.V., 1 mg, day 1
Cyclophosphamide, P.O., 100 mg/m
2
, days 1-4
Doxorubicin, I.V., 25 mg/m
2
, day 2
Prednisone, P.O., 60 mg/m
2
, days 1-4
RC - every 28 days

Pancreatic Cancer

FAM Fluorouracil, I.V., 600 mg/m
2
, days 1, 8, 29, 36
Doxorubicin, I.V., 30 mg/m
2
, days 1, 29
Mitomycin, I.V., 10 mg/m
2
, day 1
RC - every 72 days

SMF Streptozocin, I.V., 1000 mg/m
2
, days 1, 8, 29, 36
Mitomycin, I.V., 10 mg/m
2
, day 1
Fluorouracil, I.V., 600 mg/m
2
, days 1, 8, 29, 36
RC - every 72 days

Sarcoma

AC Doxorubicin, I.V., 75-90 mg/m
2
96-hour continuous infusion
Cisplatin, I.A./I.V., 90-120 mg/m
2
, 6 days
RC - every 28 days

AD Doxorubicin, I.V., 22.5 mg/m
2
/day continuous infusion, days 1-4
Dacarbazine, I.V., 225 mg/m
2
/day continuous infusion, days 1-4
RC - every 21 days

CYVADIC Cyclophosphamide, I.V., 500 mg/m
2
, day 1
Vincristine, I.V., 1.4 mg/m
2
, days 1, 5
Doxorubicin, I.V., 50 mg/m
2
, day 1
Dacarbazine, I.V., 250 mg/m
2
, days 1-5
RC - every 21 days

MAID Mesna, I.V., 2500 mg/m
2
/day continuous infusion, days 1-4
Doxorubicin, I.V., 15 mg/m
2
/day continuous infusion, days 1-4
Ifosfamide, I.V., 2500 mg/m
2
/day continuous infusion, days 1-3
Dacarbazine, I.V., 250 mg/m
2
/day continuous infusion, days 1-4
RC - every 21-28 days

VAC Vincristine, I.V., 2 mg/m
2
/week (max: 2 mg), during weeks 1-12
Dactinomycin, I.V., 0.015 mg/kg (max: 0.5 mg)
Cyclophosphamide, P.O., 2.5 mg/kg/day for 2 years