ADIPOSITY

The disease is attended with excess development

of fatty tissues. The disease usually develops after
reaching 40 years of age. It is typical of women.
Adiposity primarily results from an energy balance
disturbance, i.e. discrepancy between the amount
of energy entering the organism and its
consumption. Adiposity often arises from
hyperalimentation. It can also result from impaired
control over energy consumption. The disease may
be prompted by hereditary-constitutional
predisposition, insufficient physical activity, some
physiological states pregnancy, lactation, climax,
etc.!, and such factors as age, sex and professional
occupation. Adiposity is a hypothalamo-hypophyseal disease. Its pathogenesis centres on expressed
hypothalamic disturbances causing changes in behavioural reactions particularly, food behaviour!
and hormonal disturbances. The activity of the hypothalamo-hypophyseal-adrenal system is
increased. The adrenocorticotrophic hormone secretion rises. The hydrocortisone production speed
is increased. "etabolism is accelerated. The secretion of the somatotropic hormone featuring
lipolytic effect is reduced.
The secretion of gonadotropin and sexual steroids is impaired. It is characterised by hypersulinemia
whose efficiency is decreased. The metabolism of thyroid hormones and sensitivity of peripheral
tissues are impaired. Adiposity can be alimentary-constitutional, hypothalamic and endocrine.
Alimentary-constitutional adiposity is of family-type and, as a rule, affects the members of one
family or their blood relatives. It is caused by regular hyperalimentation, improper nutrition, lac# of
physical exercise, etc. $ypothalamic adiposity arises from a disturbance of the hypothalamic
functions and features a number of peculiar clinic characteristics. %ndocrine adiposity is one of the
first symptoms of a primary pathology of the endocrine glands, i.e. hypercorticoidism,
hypothyroidism, hypogonadism, etc. $owever, all the forms lead to certain hypothalamic
disturbances, either primary, or developing in the course of the disease progress.
&reated by 'ellness-(tudio .co.u#