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  • 001 Cytokine List

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    Gameron777
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    This document lists various cytokines and their selected activities. It shows that cytokines like IL-1, IL-6, and TNF-α are involved in processes like fever, inflammation, and acute phase reactions. Other cytokines such as IL-2, IL-3, IL-7 promote the growth and differentiation of immune cells like T cells, B cells, eosinophils. Cytokines also direct the differentiation of T helper cell subsets, with IL-12 and IFN-γ promoting a TH1 response while IL-4 drives a TH2 response.

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    Useful list of cytokines for basic sciences (immunology) for med school

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    This document lists various cytokines and their selected activities. It shows that cytokines like IL-1, IL-6, and TNF-α are involved in processes like fever, inflammation, and acute phase reactions. Other cytokines such as IL-2, IL-3, IL-7 promote the growth and differentiation of immune cells like T cells, B cells, eosinophils. Cytokines also direct the differentiation of T helper cell subsets, with IL-12 and IFN-γ promoting a TH1 response while IL-4 drives a TH2 response.

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    © All Rights Reserved
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    12 views1 page

    001 Cytokine List

    Uploaded by

    Gameron777
    This document lists various cytokines and their selected activities. It shows that cytokines like IL-1, IL-6, and TNF-α are involved in processes like fever, inflammation, and acute phase reactions. Other cytokines such as IL-2, IL-3, IL-7 promote the growth and differentiation of immune cells like T cells, B cells, eosinophils. Cytokines also direct the differentiation of T helper cell subsets, with IL-12 and IFN-γ promoting a TH1 response while IL-4 drives a TH2 response.

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    © All Rights Reserved
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    Selected Cytokines of Major Interest and Examples of Their Activities

    Cytokine Selected Activities


    IL-1 Fever, M! activation, activation vasc. endothelium, PMN mobilization
    IL-2 T cell proliferation
    IL-3 Hematopoietic growth factor for multiple WBC lineages
    IL-4 B cell activation, IgE CSR, TH2 polarization
    IL-5 Eosinophil hematopoiesis, chemotaxis, and activation
    IL-6 Fever, TH17 differentiation, acute phase reactant induction
    IL-7 Proliferation of pre-B & pre-T cells
    IL-10 Suppresses APC MHCII and B7 expression
    IL-12
    Activates NK cells, promotes IFN-" production by M!, promotes TH1
    polarization
    IL-13 B cell proliferation, inhibits M! inflammatory cytokine production
    IL-17 PMN recruitment and activation
    IL-23 Promotes TH17 differentiation
    IFN-# Proteasome induction, increased MHC I expression
    IFN-$ Proteasome induction, increased MHC I expression
    IFN-"
    M! activation, increased expression of MHC I and II and antigen
    processing components, suppression of TH2 polarization
    TNF-#
    Neutrophil mobilization, activation vasc. endothelium, increase in vasc.
    leakiness, maturation of DC's, fever, acute phase reactants
    TGF-$ Inhibits lymphocyte growth and M! activation, directs IgA class switch
    GM-CSF Hematopoietic growth factor for granulocytes and monocytes

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