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Kuliah Imun Skin Integumen
Kuliah Imun Skin Integumen
Kuliah Imun Skin Integumen
INFEKSI KULIT
dr.Budi Darma
Fakultas Kedokteran
Universitas Malahayati
2
SISTIM IMUN
NON SPESIFIK
SPESIFIK
SELULER
SEL T
HUMORAL
SEL B
FISIK/
MEKANIK
SELULER LARUT
KULIT
SELAPUT
LENDIR
SILIA
BATUK
BERSIN
ASAM LAMBUNG
LISOZIM
INTERFERON
AS NEURAMINIK
DAN LAIN-LAIN
KOMPLEMEN
INTERFERON
C REACTIVE PROTEIN
(CP)
B
I
O
K
I
M
I
A
H
U
M
O
R
A
L
-FAGOSIT :
MONOLUKLEAR
PMN
-SEL NOL : NK
K
-SEL MEDIATOR :
BASOFIL, MAST
TROMBOSIT
Th1 Th2
Ts
Td
Tc
7
Skin and mucous membranes
Anatomical barrier (epidermis, dermls)
Unsaturated fatty acids: anti-bacterial
- sebaceus glands
- skin commensals:Proplonicbacterlum acnes
Saturated fatty acid: fungistatic
Mucus :
- trap organisms
Epithelium:
- prevent penetration of large molecules
- Prevent entrance of pathogens
TERIMAKASIH