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  • KJZ Drug Interactions Reactio

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    Mahmoud Mohsen
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    The document lists various drug interactions and reactions, including induction or inhibition of cytochrome P450 enzymes, increased risk of digoxin toxicity from certain drugs, competition for albumin-binding sites between some drugs, blood disorders caused by several medications, hemolysis in glucose-6-phosphate dehydrogenase deficient patients, gynecomastia resulting from multiple drugs, Stevens-Johnson syndrome with ethosuximide and sulfonamides, photosensitivity with tetracycline and other drugs, and drug-induced lupus erythematosus from procainamide and other medications.

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    The document lists various drug interactions and reactions, including induction or inhibition of cytochrome P450 enzymes, increased risk of digoxin toxicity from certain drugs, competition for albumin-binding sites between some drugs, blood disorders caused by several medications, hemolysis in glucose-6-phosphate dehydrogenase deficient patients, gynecomastia resulting from multiple drugs, Stevens-Johnson syndrome with ethosuximide and sulfonamides, photosensitivity with tetracycline and other drugs, and drug-induced lupus erythematosus from procainamide and other medications.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    20 views1 page

    KJZ Drug Interactions Reactio

    Uploaded by

    Mahmoud Mohsen
    The document lists various drug interactions and reactions, including induction or inhibition of cytochrome P450 enzymes, increased risk of digoxin toxicity from certain drugs, competition for albumin-binding sites between some drugs, blood disorders caused by several medications, hemolysis in glucose-6-phosphate dehydrogenase deficient patients, gynecomastia resulting from multiple drugs, Stevens-Johnson syndrome with ethosuximide and sulfonamides, photosensitivity with tetracycline and other drugs, and drug-induced lupus erythematosus from procainamide and other medications.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
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    of 1

    1. Induction of P-450 enzymes Barbiturates, phenytoin, carbamazepine, rifampin, quinidine, griseofulvin.

    2. Inhibition of P-450 enzymes Cimetidine, ketoconazole, INH, grapefruit, erythromycin, sulfonamides.


    3. Metabolism by P-450
    enzymes
    Benzodiazepines, amide anestehtics, metoprolol, propranolol, nifedipine, phenytoin, quinidine,
    theophylline, warfarin, barbiturates.
    4. risk of digoxin toxicity Quinidine, cimetidine, amiodarone, CCBs.
    5. Competition for albumin-
    binding sites
    Warfarin, ASA, phenytoin.
    6. Blood dyscrasias Ibuprofen, quinidine, methyldopa, chemotherapeutic agents.
    7. Hemolysis in G6PD-deficient
    patients
    Sulfonamides, isoniazid (INH), ASA, ibuprofen, nitrofurantoin, primaquine, pyrimethamine,
    chloramphenicol.
    8. Gynecomastia "Some Excellent Drugs Create Awesome Knockers."
    Sulfonamides, Estrogens, Digitalis, Cimetidine, chronic Alcohol use, Ketoconazole
    9. Stevens-Johnson syndrome Ethosuximide, sulfonamides.
    10. Photosensitivity Tetracycline, amiodarone, sulfonamides.
    11. Drug-induced SLE Procainamide, hydralazine, INH, penicillamine, chlorpromazine, methyldopa, quinidine.
    KJZ Drug Interactions & Reactions
    Study online at quizlet.com/_3cq1p

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