Serotonin and dopamine are important neurotransmitters that interact in complex ways in the brain. In people with schizophrenia, it is theorized that an imbalance between these neurotransmitters contributes to the symptoms. Specifically, lower than normal serotonin levels may cause increased dopamine activity in the mesolimbic pathway of the brain, which is associated with the positive symptoms of schizophrenia like hallucinations and delusions. Understanding the relationship between these two neurotransmitter systems may help develop new treatment strategies for schizophrenia.
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Original Title
Serotonin, dopamine and their interactions in schizophrenia (1993)
Serotonin and dopamine are important neurotransmitters that interact in complex ways in the brain. In people with schizophrenia, it is theorized that an imbalance between these neurotransmitters contributes to the symptoms. Specifically, lower than normal serotonin levels may cause increased dopamine activity in the mesolimbic pathway of the brain, which is associated with the positive symptoms of schizophrenia like hallucinations and delusions. Understanding the relationship between these two neurotransmitter systems may help develop new treatment strategies for schizophrenia.
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Serotonin and dopamine are important neurotransmitters that interact in complex ways in the brain. In people with schizophrenia, it is theorized that an imbalance between these neurotransmitters contributes to the symptoms. Specifically, lower than normal serotonin levels may cause increased dopamine activity in the mesolimbic pathway of the brain, which is associated with the positive symptoms of schizophrenia like hallucinations and delusions. Understanding the relationship between these two neurotransmitter systems may help develop new treatment strategies for schizophrenia.
Copyright:
Attribution Non-Commercial (BY-NC)
Available Formats
Download as DOC, PDF, TXT or read online from Scribd