Notocias sobre oncogenes

Cell Death & Disease is delighted to announce it has

published its 1000th article:The traditional Chinese
medical compound Rocaglamide protects non-
malignant primary cells from DNA damage-induced
toxicity by inhibition of p53 expression.
Read more about the accomplishments of the journal
in the Editorials by Eric H. Baehrecke and Gerry
Melino. To mark this achievement, we have published
a web focus from Cell Death & Disease and Cell Death
and Differentiation on anti-cancer
therapies. Submit your paper to the only journal
which provides centre stage to fundamental, disease-
orientated and translational research in cell death and
receive an excellent author experience.
The future of next generation sequencing?
A web focus from European Journal of Human
Genetics and Oncogene
Next generation sequencing is rapidly pervading all
areas of Human genetics: improving speed, precision,
and last but not least breadth of diagnostics; opening
up new avenues of screening; are screening and
testing still different or is there a confluence? In
parallel, it profoundly affects basic biology discovery
by unravelling mutation mechanisms and causes and
consequences in gene regulation and what goes
wrong in genetic disease and cancer. Besides many
insights, the data deluge also brings questions: on
how to handle this, internally and towards the
patients; the role of geneticists in the process; how -
and if - to integrate direct to consumer services; how
to maintain a proper public-private balance to allow
therapy development but avoid undue restrictions in
data access.
Follow the contributions to this debate in European
Journal of Human Geneticsand Oncogene.
'Open' option for authors
Oncogene offers authors the option to publish their
articles with immediate open access upon publication.
Open access articles will also be deposited on PubMed
Central at the time of publication and will be freely
available immediately. Find out more from our FAQs
page.
Using animals properly
Read the updated guidelines on the welfare and use
of animals in cancer research. All experiments should
incorporate the 3Rs: replacement, reduction and
refinement. Recommendations in this BJC article
include topics in study design, choice of tumor
models, and humane endpoints.