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Allergies:

Type1hypersensitivityreaction
IgEmediated
3phases:
1.Sensitization:allergeninducesIgEformation
2.IgEprimesmastcells
3.SubsequentexposuretoallergencrosslinksIgEtocausemastcelldegranulation(histamine,leukotrienes)
1ststepinmanagement:AVOIDAllergen/trigger

Anaphylaxis

systemicrxn
Causedbyfoodallergy,insectvenom,drugallergy

w/in30mins:
Pruritis,flushing,angioedema

Dyspnea,wheezing

Anaphylacticshock
Epinephrine
AllergicRhinitis

nasalmucosaishypersensitvie
toinhaledallergens
Seasonaloutdoor

continuousindoor(pets,dustmites)

nasalcongestion,itching
Intranasalsteroid(flonase)

Antihistamine(2ndgencertrizine)
Atopicdermatitis(Eczema)

skinishypersensitive
Pruritis

Acute:erythema,crusting

Chronic:Lichenification(fromconstantitching),
hyperpigmentation

Infants:face&truncal
Kids:flexors

complication:highriskforskininfection
Corticosteroidcream

Antihistamines

Baths:Tepidwater,dryskin,lather
lubricant
Foodallergy Mostcommon:egg,milk,peanut,soy,wheat,fish

Oralwelling
GI(vomitting,diarrhea)
Resp
Urticaria
Anaphylaxis
Exclusivebreastfeedingfor6mo
foodallergies
Insectvenomallergy Common:fireants,bees,yellowjackets

range:localizedanaphylaxis
Localskinrxn:coldcompress,
analgesic,antihistamine
Utricaria(Hives) circumscribed,raisededemapruritic

causes:
foods
contact
drugs
infection
insect
Antihistamine
DrugAllergy Mostcommon:penicillin,aspirin,NSAIDs,narcotics

Utricaria,angiedema,anaphylaxis
treatutricaria,anphylaxis
Asthmalookatrespnotes
Atopicmarch:
EczemaGIdisorders,wheezing(RAD)RhinitisAsthmaAdultasthma

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