Researchers found that triglycerides, a type of fat found in junk food, act on the brain in the same way as drugs, exposing an epidemic of inadvertent drug addiction through the standard American diet. Tests on mice found that those given triglycerides were less motivated to seek more food and had reduced cravings, while mice not given triglycerides were more compulsive in obtaining food, similar to drug addicts seeking their next fix. The brain responds to fat intake the same as it does to hard drugs, and many obese people have high triglyceride levels in their blood and brain, making them addicted to triglycerides and unhealthy foods in the same way as drug addiction.
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Triglycerides in mm Junk Food Are the Chemical Equivalent Of
Researchers found that triglycerides, a type of fat found in junk food, act on the brain in the same way as drugs, exposing an epidemic of inadvertent drug addiction through the standard American diet. Tests on mice found that those given triglycerides were less motivated to seek more food and had reduced cravings, while mice not given triglycerides were more compulsive in obtaining food, similar to drug addicts seeking their next fix. The brain responds to fat intake the same as it does to hard drugs, and many obese people have high triglyceride levels in their blood and brain, making them addicted to triglycerides and unhealthy foods in the same way as drug addiction.
Researchers found that triglycerides, a type of fat found in junk food, act on the brain in the same way as drugs, exposing an epidemic of inadvertent drug addiction through the standard American diet. Tests on mice found that those given triglycerides were less motivated to seek more food and had reduced cravings, while mice not given triglycerides were more compulsive in obtaining food, similar to drug addicts seeking their next fix. The brain responds to fat intake the same as it does to hard drugs, and many obese people have high triglyceride levels in their blood and brain, making them addicted to triglycerides and unhealthy foods in the same way as drug addiction.
Triglycerides in junk food are the chemical equivalent of
'hard drugs' for the brain
Wednesday, April 16, 2014 by: Ethan A. Huff, staff writer Tags: triglycerides, junk food, hard drugs (NaturalNews) Millions of Americans who claim to be opposed to drug use are actually heavy drug users themselves, according to a new study out of France. Researchers from the University of Paris' Functional and Adaptive Biology laboratory recently found that triglycerides, a type of fat often found in junk foods, act on the brain in the same manner as many street drugs, exposing an epidemic of inadvertent drug addiction via the standard American diet. Serge Luquet and his team, publishing their findings in the April 15, 2014, issue of the journal Molecular Psychiatry, tested the effects of triglycerides on mice. Having previously learned that these lipid compounds stimulate certain areas of the brain associated with pleasure and reward, the team decided to see how mice reacted to having a steady supply of triglycerides infused directly into their brains.
A body conditioned to high fat intake will constantly seek it out like a drug fix Compared to mice not receiving the triglycerides, the test mice were less motivated than control mice to seek out more food, indicating a dose-response effect from consuming the fats. All the mice were allowed to access special levers that dispensed various food rewards, but those mice given the triglycerides were less likely to have brain activity telling them to eat more.
On the flip side, the mice not given triglycerides were found to be much more compulsive when it came to getting their food. Much in the same way that drug addicts have to constantly seek out their next "fix" in order to function, the control mice, who like all mice naturally desire high-fat, high-sugar foods, tended toward obsessively craving the food rewards. "Triglycerides, fatty substances from food, may act in our brains directly on the reward circuit, the same circuit that is involved in drug addiction," reads a summary of the report.
Brain responds to fat intake the same way it responds to hard drugs Using a fluorescence microscope to analyze the mice's individual brain activity, the research team was able to ascertain a specific enzyme in the brain that decomposes triglycerides, producing feelings of pleasure and satisfaction. When this enzyme is removed or deactivated, as the researchers did with the test mice, the desire for fatty foods becomes insatiable, much in the same way that a drug addict goes through withdrawals when cut off from his preferred substances. Interestingly, the infused mice tended toward reduced physical activity and decreased likelihood of balancing a diet of both high-fat foods and simpler foods, compared to control mice who were obsessed with trying to gain access to the fats.
Many obese people are 'drug' addicts to triglycerides, unhealthy foods In the end, this constant desire for fatty foods can lead to binge eating and gluttony, which in turn results in obesity for many people. Not surprisingly, obese individuals tend to have excessively high levels of triglycerides in both their blood and brain, and are typically more sedentary than the average person. "With obesity, blood (and therefore brain) triglyceride levels are higher than average," reads a ScienceDaily.com summary of the study's outcomes. "So obesity is often associated with overconsumption of sugary, fatty foods. ... At high triglyceride contents, the brain adapts to obtain its reward, similar to the mechanisms observed when people consume drugs."
NaturalNews) Jutaan orang Amerika yang mengaku akan menentang penggunaan narkoba adalah pengguna narkoba sebenarnya berat sendiri, menurut sebuah studi baru dari Perancis. Peneliti dari University of Paris 'Fungsional dan Adaptive Biologi laboratorium baru-baru ini menemukan bahwa trigliserida, jenis lemak yang sering ditemukan dalam makanan junk, bertindak pada otak dengan cara yang sama seperti banyak narkoba, memperlihatkan epidemi kecanduan narkoba sengaja melalui standar diet Amerika.
Serge Luquet dan timnya, menerbitkan temuan mereka di 15 April, 2014, jurnal Molecular Psychiatry, menguji efek trigliserida pada tikus. Setelah sebelumnya belajar bahwa senyawa ini lipid merangsang daerah-daerah tertentu dari otak yang berhubungan dengan kesenangan dan penghargaan, tim memutuskan untuk melihat bagaimana tikus bereaksi untuk memiliki pasokan trigliserida diinfus langsung ke otak mereka.
Tubuh dikondisikan untuk asupan lemak tinggi akan terus mencari itu keluar seperti memperbaiki narkoba
Dibandingkan dengan tikus yang tidak menerima trigliserida, tikus uji yang kurang termotivasi daripada tikus kontrol untuk mencari lebih banyak makanan, yang menunjukkan efek dosis-respon dari mengkonsumsi lemak. Semua tikus diizinkan untuk mengakses tuas khusus yang dibagikan berbagai hadiah makanan, tetapi mereka tikus yang diberi trigliserida kurang cenderung memiliki aktivitas otak memberitahu mereka untuk makan lebih banyak.
Di sisi lain, tikus yang tidak diberi trigliserida ditemukan untuk menjadi jauh lebih kompulsif ketika datang untuk mendapatkan makanan mereka. Banyak cara yang sama bahwa pecandu narkoba harus terus-menerus mencari mereka berikutnya "memperbaiki" untuk fungsi, tikus kontrol, yang seperti semua tikus secara alami keinginan tinggi lemak, makanan tinggi gula, cenderung ke arah obsesif keinginan imbalan makanan.
"[T] riglycerides, zat lemak dari makanan, dapat bertindak dalam otak kita langsung di sirkuit reward, sirkuit yang sama yang terlibat dalam kecanduan narkoba," membaca ringkasan laporan.
Otak merespon asupan lemak dengan cara yang sama menanggapi obat keras
Menggunakan mikroskop fluoresensi untuk menganalisa aktivitas otak individu tikus, tim peneliti mampu memastikan enzim tertentu di otak yang terurai trigliserida, menghasilkan perasaan senang dan kepuasan. Bila enzim ini dihapus atau dinonaktifkan, sebagai peneliti lakukan dengan tikus percobaan, keinginan untuk makanan berlemak menjadi tak terpuaskan, banyak cara yang sama bahwa pecandu narkoba berjalan melalui penarikan ketika terputus dari zat yang disukainya. Menariknya, tikus diresapi cenderung ke arah penurunan aktivitas fisik dan penurunan kemungkinan menyeimbangkan diet dari kedua makanan tinggi lemak dan makanan sederhana, dibandingkan dengan kontrol tikus yang terobsesi dengan mencoba untuk mendapatkan akses ke lemak. Banyak orang obesitas 'obat' pecandu trigliserida, makanan tidak sehat Pada akhirnya, keinginan konstan untuk makanan berlemak dapat menyebabkan pesta makan dan kerakusan, yang pada gilirannya menghasilkan obesitas bagi banyak orang. Tidak mengherankan, orang gemuk cenderung memiliki tingkat yang terlalu tinggi trigliserida dalam darah dan otak mereka, dan biasanya lebih banyak duduk daripada rata-rata orang. "Tingkat [W] engan obesitas, darah (dan karena itu otak) trigliserida lebih tinggi dari rata-rata," membaca ringkasan ScienceDaily.com hasil studi tersebut. "Jadi obesitas sering dikaitkan dengan berlebihan dari manis, makanan berlemak. ... Pada isi trigliserida tinggi, otak beradaptasi untuk memperoleh hadiah, mirip dengan mekanisme diamati ketika orang mengkonsumsi obat-obatan." Anda dapat membaca siaran pers penuh kuliah di universitas ini: http://www2.cnrs.fr.
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